BioMed Research International

Hepatocellular Carcinoma: Carcinogenesis, Establishment, Progression, and Therapies


Publishing date
28 Mar 2014
Status
Published
Submission deadline
08 Nov 2013

Lead Editor

1State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China

2Suez Canal University, Suez Canal Medical School, Ismailia, Egypt

3Department of Oncology and Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China

4Department of Pediatrics and Simon Cancer Center Indiana University School of Medicine, USA


Hepatocellular Carcinoma: Carcinogenesis, Establishment, Progression, and Therapies

Description

Globally, hepatocellular carcinoma (HCC) has had a continuous increase in incidence over the last two decades. Its development has a complicated process and correlates to numerous factors including hepatitis viruses, intoxication, diabetes, obesity, and smoking. Hepatitis virus B and C have long been related to the etiology of HCC and long-time liver cirrhosis resulted from hepatitis B/C virus infection is responsible for its establishment and progression in a multistep process. Recently, HCC has been reported to be promoted by bacterial translocation implying the potential of chemoprevention. Molecular links are also identified, which characterize tumorigenic intracellular pathways and suggest molecular targeted therapies. There are many therapeutic modalities for treatment of HCC but evidence-based approach to the multidisciplinary management is of paramount importance.

We invite authors to contribute original research and review articles that will stimulate the lasting exertion to unveil the mechanism of HCC development and progression, with special interest in articles that cast new insights into HCC establishment and management. Potential topics include, but are not limited to:

  • Recent developments in early diagnosis of HCC
  • Advances in liver cirrhosis risks, imaging, and management
  • Chemoprevention of liver carcinogenesis
  • Curative therapy and prevention of recurrence
  • Transjugular intrahepatic portosystemic shunt as a bridge for liver transplantation
  • Transcatheter arterial chemoembolization
  • Radiofrequency ablation of HCC
  • Laparoscopic microwave coagulation therapy for HCC
  • Biomarkers for diagnosis of HCC
  • Antiviral therapy for prevention of postoperative recurrence
  • p53 gene therapy of HCC
  • Multifactors for hepatocarcinogenesis
  • Inflammation and HCC
  • Recent advances in comprehensive treatment of HCC

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/hepatology/hccs/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 706142
  • - Editorial

Hepatocellular Carcinoma: Carcinogenesis, Establishment, Progression, and Therapies

Yong-Song Guan | Mohammad Ahmad Al-Shatouri | ... | Wei Mike Liu
  • Special Issue
  • - Volume 2014
  • - Article ID 239706
  • - Research Article

Diagnosis System for Hepatocellular Carcinoma Based on Fractal Dimension of Morphometric Elements Integrated in an Artificial Neural Network

Dan Ionuț Gheonea | Costin Teodor Streba | ... | Ion Rogoveanu
  • Special Issue
  • - Volume 2014
  • - Article ID 241571
  • - Research Article

Adhesion of Pancreatic Cancer Cells in a Liver-Microvasculature Mimicking Coculture Correlates with Their Propensity to Form Liver-Specific Metastasis In Vivo

Mohammad Mahfuz Chowdhury | Mathieu Danoy | ... | Yasuyuki Sakai
  • Special Issue
  • - Volume 2014
  • - Article ID 806391
  • - Clinical Study

Multidisciplinary Management of Hepatocellular Carcinoma in Clinical Practice

Gemma Bruera | Katia Cannita | ... | Enrico Ricevuto
  • Special Issue
  • - Volume 2014
  • - Article ID 384121
  • - Research Article

Synergistic Effect of MiR-146a Mimic and Cetuximab on Hepatocellular Carcinoma Cells

Suning Huang | Rongquan He | ... | Gang Chen
  • Special Issue
  • - Volume 2014
  • - Article ID 153867
  • - Review Article

Involvement of DNA Damage Response Pathways in Hepatocellular Carcinoma

Sheau-Fang Yang | Chien-Wei Chang | ... | Yao-Tsung Yeh
  • Special Issue
  • - Volume 2014
  • - Article ID 797898
  • - Review Article

Therapeutic Potential of MicroRNA: A New Target to Treat Intrahepatic Portal Hypertension?

Can-Jie Guo | Qin Pan | ... | Xiong Ma
  • Special Issue
  • - Volume 2014
  • - Article ID 194278
  • - Clinical Study

Transarterial Chemoembolization for the Treatment of Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: Prognostic Factors in a Single-Center Study of 188 Patients

Lei Liu | Cheng Zhang | ... | Guohong Han
  • Special Issue
  • - Volume 2014
  • - Article ID 735672
  • - Review Article

mTOR in Viral Hepatitis and Hepatocellular Carcinoma: Function and Treatment

Zhuo Wang | Wei Jin | ... | Xian Wang
  • Special Issue
  • - Volume 2014
  • - Article ID 486407
  • - Review Article

MicroRNAs in Hepatocellular Carcinoma: Carcinogenesis, Progression, and Therapeutic Target

Chao-Hung Hung | Yi-Chun Chiu | ... | Tsung-Hui Hu
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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