BioMed Research International

Diabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Avenues


Status
Published

1University of Exeter Medical School, Exeter, UK

2University of Bristol, Bristol, UK

3University of Turin, Turin, Italy

4University of Leiden, Leiden, Netherlands


Diabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Avenues

Description

Diabetic nephropathy (DN) is the most common cause of dialysis-dependent renal failure in the developed world. Multiple molecular mechanisms of DN progression have been described in recent years; however, mechanism-derived treatments for DN are still lacking, partly due to poor understanding of the detailed molecular mechanisms underlying diabetic complications. In this issue we intend to focus on the new advances in our knowledge of DN pathogenesis as well as novel ideas for specific treatments.

We, thus, invite investigators to contribute with original research articles, as well as review articles, that seek to explore the pathological manifestations, molecular mechanisms, and innovative pharmacological strategies aimed at its prevention/management.

Potential topics include but are not limited to the following:

  • Novel molecules, signaling pathways, mechanisms implicated in DN pathogenesis
  • New therapeutic avenues/development of specific treatments
  • Advances in histopathology of DN
  • Novel animal models to study DN
  • Novel biomarkers for early diagnosis and prognosis prediction
  • Metabolomics, analytical, and computational approaches to DN
  • New clinical management strategies

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 3146524
  • - Editorial

Diabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Avenues

Sebastian Oltean | Richard Coward | ... | Hans Baelde
  • Special Issue
  • - Volume 2017
  • - Article ID 3982906
  • - Research Article

CYLD Deubiquitinase Negatively Regulates High Glucose-Induced NF-κB Inflammatory Signaling in Mesangial Cells

Yanhui Li | Wei Huang | ... | Yong Xu
  • Special Issue
  • - Volume 2017
  • - Article ID 2682861
  • - Research Article

Protective Effects of Pyridoxamine Supplementation in the Early Stages of Diet-Induced Kidney Dysfunction

F. Chiazza | A. S. Cento | ... | M. Collino
  • Special Issue
  • - Volume 2017
  • - Article ID 1909258
  • - Review Article

Molecular Mechanisms and Treatment Strategies in Diabetic Nephropathy: New Avenues for Calcium Dobesilate—Free Radical Scavenger and Growth Factor Inhibition

Hermann Haller | Linong Ji | ... | Jan Menne
  • Special Issue
  • - Volume 2017
  • - Article ID 4691389
  • - Research Article

Urinary Neutrophil Gelatinase-Associated Lipocalin Is Complementary to Albuminuria in Diagnosis of Early-Stage Diabetic Kidney Disease in Type 2 Diabetes

Agnieszka Gala-Błądzińska | Paulina Dumnicka | ... | Marek Kuźniewski
  • Special Issue
  • - Volume 2017
  • - Article ID 5724069
  • - Review Article

Antiangiogenic Therapy for Diabetic Nephropathy

Katsuyuki Tanabe | Yohei Maeshima | ... | Jun Wada
  • Special Issue
  • - Volume 2017
  • - Article ID 1516985
  • - Research Article

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling

Miaomiao Lu | Nanchang Yin | ... | Ermin Wang
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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