BioMed Research International

ECM-Like Scaffolds: Nature Drives Research


Publishing date
15 Aug 2014
Status
Published
Submission deadline
28 Mar 2014

1Department of Industrial Engineering, University of Rome “Tor Vergata”, Rome, Italy

2The Workers Compensation Authority (INAIL), Rome, Italy

3Surgery Unit, UCL Institute of Child Health, London, UK


ECM-Like Scaffolds: Nature Drives Research

Description

The fabrication of a suitable scaffold for organ and/or tissue regeneration is a crucial starting point for an effective tissue engineering approach. For this aim, an accurate morphological, biochemical, and mechanical replication of the tissue-specific extracellular matrix (ECM) to be regenerated can effectively contribute to elicit a positive cell response, tissue formation, and, therefore, proper host integration after implantation. To further enhance this function, several technical strategies can be usefully planned, including innovative fabrication techniques, surface modification, incorporation of specific fillers, and/or addition of drugs or growth factors to be subsequently released to speed up the autologous tissue regeneration. In this regard, many experimental approaches have been published so far, and maybe it is time to open a discussion on the results that can lead to an advanced clinical treatment.

We invite investigators to submit original research and review articles, mainly focusing on the next research directions and suggesting “ideas for the future,” to actually contribute to the development of this research area. The presentation of fabrication techniques that can finely reproduce the natural ECM of the treated anatomical district, the detailed investigation of the cell-scaffold interaction, and the evaluation of novel tissue guided by the substrate should be focused on in this special issue. Moreover, in order to present the state of the art and, most importantly, to furnish a perspective, but realistic, scenario of the potential of this topic, we are particularly interested in articles describing preclinical and early clinical trials. Potential topics include, but are not limited to:

  • Fabrication techniques to produce ad hoc natural-derived and/or synthetic ECM-like scaffolds
  • Innovative approaches for a detailed characterization of tissue-specific scaffold properties
  • Influence of the substrate in dictating the cell response
  • Smart strategies to reproduce biomechanical and biochemical cues of the natural ECM
  • In vivo assessment to reliably move from bench to bedside

Before submission authors should carefully read over the journal’s Author Guidelines which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/tissue.engineering/scaf/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 298361
  • - Editorial

ECM-Like Scaffolds: Nature Drives Research

Costantino Del Gaudio | Silvia Baiguera | ... | Luca Urbani
  • Special Issue
  • - Volume 2014
  • - Article ID 398069
  • - Review Article

Tissue Engineered Scaffolds for an Effective Healing and Regeneration: Reviewing Orthotopic Studies

Silvia Baiguera | Luca Urbani | Costantino Del Gaudio
  • Special Issue
  • - Volume 2014
  • - Article ID 762189
  • - Research Article

Tailored PVA/ECM Scaffolds for Cartilage Regeneration

Elena Stocco | Silvia Barbon | ... | Claudio Grandi
  • Special Issue
  • - Volume 2014
  • - Article ID 762705
  • - Review Article

Biological Effects of Spirulina (Arthrospira) Biopolymers and Biomass in the Development of Nanostructured Scaffolds

Michele Greque de Morais | Bruna da Silva Vaz | ... | Jorge Alberto Vieira Costa
  • Special Issue
  • - Volume 2014
  • - Article ID 685426
  • - Research Article

Blood Vessel-Derived Acellular Matrix for Vascular Graft Application

Luigi Dall’Olmo | Ilenia Zanusso | ... | Maria Teresa Conconi
  • Special Issue
  • - Volume 2014
  • - Article ID 161437
  • - Research Article

Image-Based Three-Dimensional Analysis to Characterize the Texture of Porous Scaffolds

Diana Massai | Francesco Pennella | ... | Umberto Morbiducci
  • Special Issue
  • - Volume 2014
  • - Article ID 796519
  • - Research Article

Experimental Study of Diffusion Coefficients of Water through the Collagen: Apatite Porosity in Human Trabecular Bone Tissue

Franco Marinozzi | Fabiano Bini | ... | Andrea Marinozzi
  • Special Issue
  • - Volume 2014
  • - Article ID 756078
  • - Review Article

Extracellular Matrix Modulates Angiogenesis in Physiological and Pathological Conditions

Anna Neve | Francesco Paolo Cantatore | ... | Domenico Ribatti
  • Special Issue
  • - Volume 2014
  • - Article ID 652432
  • - Research Article

Novel Scaffolds Fabricated Using Oleuropein for Bone Tissue Engineering

Hui Fan | Junfeng Hui | ... | Hui Li
BioMed Research International
 Journal metrics
Acceptance rate30%
Submission to final decision71 days
Acceptance to publication36 days
CiteScore2.410
Impact Factor2.197
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