BioMed Research International

Chronic Wounds with Emphasis in Diabetic Foot Ulcers


Publishing date
15 Feb 2013
Status
Published
Submission deadline
28 Sep 2012

1Center for Genetic Engineering and Biotechnology, Havana, Cuba

2College of Medicine, University of Arizona, USA

3Institute for Wound Research, University of Florida, USA


Chronic Wounds with Emphasis in Diabetic Foot Ulcers

Description

Chronic wounds are recognized as a silent epidemic that affects a large fraction of the world’s population. Despite years of intense research, the molecular and cellular mechanisms underlying the onset and perpetuation of impaired healing of chronic wounds are still only partially understood.

Clinical data generally show that the longer a wound persists the less likely it is to heal. Thus, multiple hypotheses have been raised to decode the molecular and cellular environments of wounds chronification.

To further advance the understanding of the pathology of chronic wounds, especially diabetic foot ulcers, and enhance translation of this basic knowledge into improved clinical care, the Journal of Biomedicine and Biotechnology will publish a special issue that is broadly focused on wound healing and tissue repair. Potential topics include, but are not limited to:

  • Epidemiology of chronic wounds and diabetic foot ulcers
  • Molecular toxicity of hyperglycemia or high glucose concentration on cutaneous cells (AGE/RAGE system): fibroblasts, endothelial cells, and keratinocytes
  • Molecular linkage between glucose toxicity and arrest of fibroblasts and keratinocytes
  • Diabetes, mitochondrial activity, and cutaneous cells aging and/or arrest
  • Signaling and networking of PI3kinae, Akt, mTOR, and cells proliferation in chronic wounds
  • Mechanisms of cells aging and apoptosis in chronic wounds
  • Animal models of chronic wounds
  • Molecular markers of wound chronicity or predictors for wound healing
  • Rapid point-of-care diagnostic tests for biomarkers of impaired wound healing
  • Roles of biofilms in wound failure
  • Molecular bases of reepithelialization failure
  • Modern clinical approaches to treatment of chronic wounds
  • Pharmacological interventions to modulate inflammation and proteolysis in diabetic, pressure ulcers, and other chronic wounds
  • Perspectives for growth factors and other soluble messengers, clinical trials
  • Advances in negative pressure wound treatment (NPWT)
  • Advances in natural and synthetic acellular matrix dressings
  • Advances in hyperbaric oxygen and topical NO treatments
  • Autologous and allogenic stem cells in chronic wound healing - clinical trials and laboratory research

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 890352
  • - Editorial

Chronic Wounds with Emphasis in Diabetic Foot Ulcers

Jorge Berlanga-Acosta | David G. Armstrong | ... | Luis Herrera-Martinez
  • Special Issue
  • - Volume 2013
  • - Article ID 963457
  • - Research Article

Revealing the Mechanism of In Vitro Wound Healing Properties of Citrus tamurana Extract

Madhyastha Harishkumar | Yamaguchi Masatoshi | ... | Maruyama Masugi
  • Special Issue
  • - Volume 2013
  • - Article ID 385641
  • - Review Article

Current Aspects in the Pathophysiology and Treatment of Chronic Wounds in Diabetes Mellitus

Elena Tsourdi | Andreas Barthel | ... | Stefan R. Bornstein
  • Special Issue
  • - Volume 2013
  • - Article ID 837620
  • - Research Article

Treatment of Nonhealing Diabetic Lower Extremity Ulcers with Skin Graft and Autologous Platelet Gel: A Case Series

Yuan-Sheng Tzeng | Shou-Cheng Deng | ... | Thierry Burnouf
  • Special Issue
  • - Volume 2013
  • - Article ID 159157
  • - Review Article

Antimicrobial Photodynamic Therapy for Methicillin-Resistant Staphylococcus aureus Infection

Xiu-jun Fu | Yong Fang | Min Yao
  • Special Issue
  • - Volume 2013
  • - Article ID 190486
  • - Review Article

Vasculogenic Cytokines in Wound Healing

Victor W. Wong | Jeffrey D. Crawford
  • Special Issue
  • - Volume 2013
  • - Article ID 389792
  • - Research Article

The Influence of Flightless I on Toll-Like-Receptor-Mediated Inflammation in a Murine Model of Diabetic Wound Healing

Nadira Ruzehaji | Stuart J. Mills | ... | Allison J. Cowin
  • Special Issue
  • - Volume 2013
  • - Article ID 754802
  • - Review Article

Abnormal Cell Responses and Role of TNF- in Impaired Diabetic Wound Healing

Fanxing Xu | Chenying Zhang | Dana T. Graves
  • Special Issue
  • - Volume 2013
  • - Article ID 719570
  • - Research Article

Low Circulating Protein C Levels Are Associated with Lower Leg Ulcers in Patients with Diabetes

K. Whitmont | G. Fulcher | ... | C. J. Jackson
  • Special Issue
  • - Volume 2013
  • - Article ID 256043
  • - Review Article

Glucose Toxic Effects on Granulation Tissue Productive Cells: The Diabetics’ Impaired Healing

Jorge Berlanga-Acosta | Gregory S. Schultz | ... | Luis Herrera-Martínez
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore4.100
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Impact Factor3.411
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