BioMed Research International

Mass Spectrometry Applications in Biomedical Research


Publishing date
26 Dec 2014
Status
Published
Submission deadline
08 Aug 2014

Lead Editor

1Department of Pathology, Albert Einstein College of Medicine, Bronx, New York 10461, USA

2School of Life Sciences, Tsinghua University, Beijing, China

3Division of Systems Biology, National Center for Toxicological Research, US FDA, Jefferson, AR 72079, USA

4Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute at Lake Nona, Orlando, FL 32827, USA


Mass Spectrometry Applications in Biomedical Research

Description

With the tremendous advances of modern mass spectrometry (MS) techniques, MS has become one of the essential analytical tools to biological and biomedical research. Mass spectrometry provides rapid and sensitive qualitative and quantitative analysis of biomolecules (proteins, peptides, oligosaccharides, lipids, DNA, and RNA), drugs, and metabolites. In combination with a variety of modern separation technologies, MS has been successfully applied to high-throughput proteomewide analysis of proteins, protein-protein interactions, and protein posttranslational modifications (PTMs) in cells, tissues, or organs. In the past several years, we have also witnessed fast growth in metabolomics and tissue imaging fueled by MS analysis. The wide implementation of MS certainly has resulted in and will continuously benefit in the advancement of indepth understanding of biological processes and their underlying molecular mechanisms. In terms of biomarker discovery for many human diseases and therapeutics, MS-based proteomics and metabolomics are playing an important role and the application of MS to clinical molecular diagnosis will be expected in the near future. Potential topics in a variety of method development and applications of MS in biological and biomedical research include, but are not limited to:

  • Proteome profile and/or quantitative proteomic studies (stable isotopic labeling, label free, and MRM)
  • Protein PTM characterization; Omics of PTMs (phosphoproteome, glycoproteome, acetylome, methylproteome, etc.)
  • MS-based biomarker discovery and/or validation
  • Metabolomics
  • MS in pharmacology and toxicology

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biochemistry/sab/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 827370
  • - Editorial

Mass Spectrometry Applications in Biomedical Research

Fa-Yun Che | Hai-Teng Deng | Shi-Jian Ding
  • Special Issue
  • - Volume 2015
  • - Article ID 354671
  • - Review Article

Metabolomics for Biomarker Discovery: Moving to the Clinic

Aihua Zhang | Hui Sun | ... | Xijun Wang
  • Special Issue
  • - Volume 2015
  • - Article ID 169234
  • - Research Article

Mass Spectrometry in Pharmacokinetic Studies of a Synthetic Compound for Spinal Cord Injury Treatment

María Sánchez-Sierra | Isabel García-Álvarez | ... | Ernesto Doncel-Pérez
  • Special Issue
  • - Volume 2015
  • - Article ID 136941
  • - Research Article

MALDI-TOF Mass Array Analysis of Nell-1 Promoter Methylation Patterns in Human Gastric Cancer

Changlu Gao | Qian Zhang | ... | Qifan Zhang
  • Special Issue
  • - Volume 2015
  • - Article ID 134050
  • - Research Article

Identification of Glioblastoma Phosphotyrosine-Containing Proteins with Two-Dimensional Western Blotting and Tandem Mass Spectrometry

Tianyao Guo | Xiaowei Wang | ... | Xianquan Zhan
  • Special Issue
  • - Volume 2015
  • - Article ID 586309
  • - Research Article

Magnetic Bead-Based Serum Peptidome Profiling in Patients with Gestational Diabetes Mellitus

Tingting Ai | Feng Chen | ... | Jiuxiang Lin
  • Special Issue
  • - Volume 2015
  • - Article ID 697958
  • - Research Article

Mass Spectral Profile for Rapid Differentiating Beta-Lactams from Their Ring-Opened Impurities

Hecheng Wang | Haiwei Huang | ... | Shengyuan Xiao
  • Special Issue
  • - Volume 2015
  • - Article ID 845041
  • - Research Article

Global Methylation and Hydroxymethylation in DNA from Blood and Saliva in Healthy Volunteers

Lode Godderis | Caroline Schouteden | ... | Kirsten Van Landuyt
  • Special Issue
  • - Volume 2015
  • - Article ID 164846
  • - Review Article

Mass Spectrometry-Based Proteomic Study Makes High-Density Lipoprotein a Biomarker for Atherosclerotic Vascular Disease

Chiz-Tzung Chang | Chao-Yuh Yang | ... | Chao-Jung Chen
  • Special Issue
  • - Volume 2015
  • - Article ID 343501
  • - Research Article

Potential Peripartum Markers of Infectious-Inflammatory Complications in Spontaneous Preterm Birth

Vojtech Tambor | Marie Vajrychova | ... | Juraj Lenco
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
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CiteScore4.100
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