BioMed Research International

Animal Models of Human Pathology


Publishing date
15 Mar 2011
Status
Published
Submission deadline
15 Sep 2010

Lead Editor

1Institute of Experimental Endocrinology and Oncology, National Council Research, Naples, Italy

2NeuroEndocrine Interactions in Rheumatology and Inflammatory Diseases, Santiago University Clinical Hospital, Santiago de Compostela, Spain

3Department of Molecular Virology, Immunology & Medical Genetics, The Ohio State University, Columbus, OH, USA


Animal Models of Human Pathology

Description

Based on the genetic alterations found in humans, multiple models of human pathologies have been generated in genetically engineered or drug-induced animals. These experimental models are valuable tools for understanding physiopathology of the disease and discovering novel therapeutic targets and drugs. In fact, one avenue holding tremendous potential to find therapies against human diseases is the use of intact living systems, where complex biological processes can be examined.

We invite authors to present original research articles as well as review articles that will stimulate the continuing efforts in developing animal models, ranging from invertebrates to large animals, to be used in preclinical applications, improving therapy in various fields of medicine (oncology, cardiovascular, immunology, endocrinology, brain pathologies, etc.). We are particularly interested in manuscripts that report naturally occurring, induced or engineered animal models of human diseases and their preclinical applications. Reviews that summarize all the animal models for a particular pathology, their involvement in preclinical trials, and their future on treatment practice are also particularly welcome. Potential topics include, but are not limited to:

  • Modelling retinoblastoma in rodents
  • The use of animal models in the study of obesity
  • The value of animal models for drug development in autoimmune diseases
  • The genetics of cardiovascular disease: new insights from animal models
  • Understanding pathogenesis and therapy of ataxia telangiectasia (AT) via animal models
  • Experimental animal models of rheumatoid arthritis, lupus erythematosus, and osteoarthritis
  • Small model organisms for neurodegenerative diseases
  • Large animal models of heart failure
  • The pig: a representative animal model for humans
  • Modeling human disease using the nematode Caenorhabditis elegans
  • Drosophila models of human diseases

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 939023
  • - Review Article

The Animal Model of Spinal Cord Injury as an Experimental Pain Model

Aya Nakae | Kunihiro Nakai | ... | Takashi Mashimo
  • Special Issue
  • - Volume 2011
  • - Article ID 691412
  • - Research Article

Joint Inflammation and Early Degeneration Induced by High-Force Reaching Are Attenuated by Ibuprofen in an Animal Model of Work-Related Musculoskeletal Disorder

Jeffrey B. Driban | Ann E. Barr | ... | Mary F. Barbe
  • Special Issue
  • - Volume 2011
  • - Article ID 518323
  • - Review Article

Laboratory Animal Models for Brucellosis Research

Teane M. A. Silva | Erica A. Costa | ... | Renato L. Santos
  • Special Issue
  • - Volume 2011
  • - Article ID 497841
  • - Review Article

Animal Models of Cardiovascular Diseases

Carlos Zaragoza | Carmen Gomez-Guerrero | ... | Jesus Egido
  • Special Issue
  • - Volume 2011
  • - Article ID 271694
  • - Review Article

Murine Models of Systemic Lupus Erythematosus

Daniel Perry | Allison Sang | ... | Laurence Morel
  • Special Issue
  • - Volume 2011
  • - Article ID 754857
  • - Review Article

Animal Models for Periodontal Disease

Helieh S. Oz | David A. Puleo
  • Special Issue
  • - Volume 2011
  • - Article ID 207504
  • - Review Article

The MRL/lpr Mouse Strain as a Model for Neuropsychiatric Systemic Lupus Erythematosus

Maria Gulinello | Chaim Putterman
  • Special Issue
  • - Volume 2011
  • - Article ID 396734
  • - Research Article

Long-Term Type 1 Diabetes Enhances In-Stent Restenosis after Aortic Stenting in Diabetes-Prone BB Rats

Geanina Onuta | Hendrik C. Groenewegen | ... | Jan-Luuk Hillebrands
  • Special Issue
  • - Volume 2011
  • - Article ID 252141
  • - Methodology Report

Assessment of Elastase-Induced Murine Abdominal Aortic Aneurysms: Comparison of Ultrasound Imaging with In Situ Video Microscopy

Junya Azuma | Lars Maegdefessel | ... | Philip S. Tsao
  • Special Issue
  • - Volume 2011
  • - Article ID 318346
  • - Research Article

Blood-Oxygenation-Level-Dependent-(BOLD-) Based R2 MRI Study in Monkey Model of Reversible Middle Cerebral Artery Occlusion

Jing Zhang | Ying-min Chen | Yun-ting Zhang
BioMed Research International
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Acceptance rate8%
Submission to final decision110 days
Acceptance to publication24 days
CiteScore5.300
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