BioMed Research International

The Threat of Antibiotics and Heavy Metal Pollution to Human Health and Potential Solutions


Publishing date
01 Apr 2020
Status
Published
Submission deadline
15 Nov 2019

Lead Editor
Guest Editors

1Chinese Academy of Sciences, Xiamen, China

2Guizhou Medical University, Guiyang, China

3Agriculture and Agri-Food Canada & Université Laval, Laval, Canada


The Threat of Antibiotics and Heavy Metal Pollution to Human Health and Potential Solutions

Description

As a result of rapid human population growth worldwide, the relationship between global human health and the environment has been explored in greater depth in recent years. Antibiotic abuse with the intent of protecting the health of humans and animals may accelerate the development of antibiotic resistance genes (ARGs) and antibiotic resistant microorganisms (ARMs) which pose health risks to humans, i.e., transfer of vancomycin resistance intestinal enterococci from exposed animals to the human population. A wide variety of ARGs, i.e., sulfonamides, tetracycline, and quinolone resistance genes, have been found in microorganisms throughout water, soil, and air.

There are coselection processes between antibiotic and heavy metal resistance. The underlying coselection mechanisms include (1) different resistance determinants present on the same gene, (2) the same genetic determinant responsible for the resistance to antibiotics and heavy metals, and (3) indirect but shared regulatory responses to antibiotics and heavy metal exposure which is also a potential coselection mechanism. Therefore, heavy metal contamination represents a long-standing selection pressure on the maintenance and spread of ARGs, with both environmental and clinical importance. Heavy metals have also led to their own concerns over their risks on human health and the environment. Although numerous studies have been conducted to address antibiotics, heavy metals and health risks, information remains limited in quite a few aspects of the integrated study of environment and clinical studies with regards to antibiotics and heavy metals. Emerging medicines and technologies that improve human health, especially that can reduce the risk of antibiotic and heavy metal resistance are rare.

This special issue calls for submissions, including original research articles and review articles, that focus on the adverse effects of antibiotics and heavy metals on the environment and human health, as well as the corresponding healthcare and medical treatment strategies. We also welcome the integrated study of environment and clinical studies regarding antibiotics and heavy metals.

Potential topics include but are not limited to the following:

  • The interactions and mechanisms between antibiotics, heavy metals and human health
  • Influences of drug abuse on the environment and human health, including, but not limited to, antibiotics, and especially emerging contaminants
  • Meta-analysis, including, but not limited to, antibiotic/heavy metal resistant microorganism
  • Medicines and technologies that improve human health
  • Methods and techniques that can reduce the risk of antibiotic and heavy metal resistance

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 3208391
  • - Research Article

Efficacy of Neoadjuvant Chemotherapy with Epirubicin and Cyclophosphamide and Weekly Paclitaxel and Trastuzumab in Human Epidermal Growth Factor Receptor 2–Positive Breast Carcinoma: A Real-World Study

Mengmeng Zhang | Ling Li | ... | Haisong Yang
  • Special Issue
  • - Volume 2020
  • - Article ID 8730406
  • - Editorial

The Threat of Antibiotics and Heavy Metal Pollution to Human Health and Potential Solutions

Peng Bao | Xiu-Li Gao | Guo-Qi Wen
  • Special Issue
  • - Volume 2020
  • - Article ID 9860425
  • - Research Article

Alkyl Thiourea Functionalised Silica for the Effective Removal of Heavy Metals from Acanthopanax senticosus Extract

Hong-Li Guo | Shuo Zhang | ... | Xiu-Li Gao
  • Special Issue
  • - Volume 2020
  • - Article ID 5421269
  • - Research Article

Abundance of Multidrug Resistance Efflux Pumps in the Urinary Metagenome of Kidney Transplant Patients

Asha Rani | Ravi Ranjan | ... | David L. Perkins
  • Special Issue
  • - Volume 2020
  • - Article ID 5397838
  • - Research Article

Application of Quality Control Circle in Promoting the Use of Rubber Dams in the Root Canal Treatment of Primary Teeth

Fang Jingxian | Liu Yang | ... | Song Yingying
  • Special Issue
  • - Volume 2020
  • - Article ID 5373927
  • - Research Article

Outcome of Gynecologic Laparoendoscopic Single-Site Surgery with a Homemade Device and Conventional Laparoscopic Instruments in a Chinese Teaching Hospital

Xianghui Su | Xiaolong Jin | ... | Xiang Tang
  • Special Issue
  • - Volume 2020
  • - Article ID 2748219
  • - Research Article

Treatment of Large and Complicated Scalp Defects with Free Flap Transfer

Fanfan Chen | Hongbin Ju | ... | Guo Fu
  • Special Issue
  • - Volume 2020
  • - Article ID 1625362
  • - Research Article

Cardiac Contractility Modulation Attenuates Chronic Heart Failure in a Rabbit Model via the PI3K/AKT Pathway

Qingqing Hao | Feifei Zhang | ... | Xiaoyong Qi
  • Special Issue
  • - Volume 2019
  • - Article ID 6547019
  • - Research Article

Effect of Metformin on a Preeclampsia-Like Mouse Model Induced by High-Fat Diet

Fuchuan Wang | Guangming Cao | ... | Xiuzhen Cao
BioMed Research International
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