BioMed Research International

Normal and Pathological Placental Angiogenesis


Publishing date
28 Nov 2014
Status
Published
Submission deadline
11 Jul 2014

Lead Editor

1Inserm U1036, Institute of Life Sciences Research and Technologies, University Joseph Fourier Grenoble and Department of Medical Biochemistry, Grenoble, France

2Deptartment of Obstetrics and Gynaecology (RWH), University of Melbourne, Parkville, VIC 3052, Australia

3Inserm UMR–S 1076, Faculté de Pharmacie, Aix–Marseille University, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France


Normal and Pathological Placental Angiogenesis

Description

Placental angiogenesis is a pivotal process that establishes fetomaternal circulation, ensures efficient maternofetal exchange, plays a key mechanistic role in the elaboration of the placental villous tree, and contributes to the overall development of the placenta throughout pregnancy. Failure in these processes is tightly linked to the development of placental pathologies such as preeclampsia (PE), early pregnancy loss, and intrauterine growth restriction (IUGR). It is now well established that a close relationship exists between embryonic development and the degree of placental angiogenesis. A key discovery in the investigation on placental pathologies was the understanding that major phenotypes of PE are associated with dysregulations in antiangiogenic factors. To date, numerous insults such as maternal chemical dependency including tobacco smoke, metal element toxicity, tumorigenesis, and oxidative stress have been shown to influence pregnancy outcome by directly affecting placental angiogenesis. In the last decade, compelling advances highlighted the central role of mesenchymal stem cells/multipotent stromal cells in placental angiogenesis and brought new insights into the understanding of the fine mechanisms underlying placental angiogenesis. Also, we know now how to measure the processes of placental angiogenesis, thanks to the innovative methods developed by specialized groups in the field of placentology.

We particularly take an interest in manuscripts that report relevance of factors that regulate angiogenesis to improve prognosis, monitoring, and therapy of placental pathologies. Reviews that summarize one or different aspects around placental angiogenesis are welcome. Furthermore, papers dealing with criteria for optimal PA measurement for clinical guidance would be of great interest. Potential topics include, but are not limited to:

  • Placental angiogenesis and reproductive medicine
  • Molecular aspects of placental angiogenesis
  • Investigation of placental angiogenesis: Methods of measurement
  • Angiogenesis in tumour in the placenta
  • Metal elements in the control of placental angiogenesis
  • Smoking and placental angiogenesis
  • Influence of oxidative stress on placental angiogenesis
  • Trophoblast–derived angiogenic factors in normal and placental pathologies
  • Role of mesenchymal stem cells/multipotent stromal cells in placental angiogenesis
  • Circulating angiogenic molecules as clinical biomarkers in the predictions of pregnancy complications

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/pharmacology/ppa/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 354359
  • - Editorial

Normal and Pathological Placental Angiogenesis

Nathalie Bardin | Padma Murthi | Nadia Alfaidy
  • Special Issue
  • - Volume 2015
  • - Article ID 294954
  • - Review Article

Circulating MicroRNAs as Clinical Biomarkers in the Predictions of Pregnancy Complications

Marthe Tsochandaridis | Laurent Nasca | ... | Annie Levy-Mozziconacci
  • Special Issue
  • - Volume 2015
  • - Article ID 814543
  • - Review Article

Angiogenesis in the Placenta: The Role of Reactive Oxygen Species Signaling

Robyn D. Pereira | Nicole E. De Long | ... | Sandeep Raha
  • Special Issue
  • - Volume 2014
  • - Article ID 145846
  • - Review Article

Glucose, Insulin, and Oxygen Interplay in Placental Hypervascularisation in Diabetes Mellitus

Silvija Cvitic | Gernot Desoye | Ursula Hiden
  • Special Issue
  • - Volume 2014
  • - Article ID 653161
  • - Research Article

Enhanced Prevalence of Plasmatic Soluble MHC Class I Chain-Related Molecule in Vascular Pregnancy Diseases

Jean Baptiste Haumonte | Sophie Caillat-Zucman | ... | Pascale Paul
  • Special Issue
  • - Volume 2014
  • - Article ID 901941
  • - Review Article

Netrins and Their Roles in Placental Angiogenesis

Mbarka Dakouane-Giudicelli | Nadia Alfaidy | Philippe de Mazancourt
  • Special Issue
  • - Volume 2014
  • - Article ID 781632
  • - Research Article

Angiogenin Expression during Early Human Placental Development; Association with Blood Vessel Formation

Nadine Pavlov | Jean-Louis Frendo | ... | Josette Badet
  • Special Issue
  • - Volume 2014
  • - Article ID 314704
  • - Research Article

Antiphospholipid Antibodies in Women Undergoing In Vitro Fertilization Treatment: Clinical Value of IgA Anti-β2glycoprotein I Antibodies Determination

Odile Paulmyer-Lacroix | Laura Despierres | ... | Nathalie Bardin
  • Special Issue
  • - Volume 2014
  • - Article ID 451906
  • - Review Article

The Multiple Roles of EG-VEGF/PROK1 in Normal and Pathological Placental Angiogenesis

Nadia Alfaidy | Pascale Hoffmann | ... | Sophie Brouillet
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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