The global analysis of transcriptome provides information about the development of ocular disorders such as diabetic retinopathy and neovascular age-related macular degeneration. It provides important information about the mechanisms of disease progression. Recently, beside genetical factors, epigenetic mechanisms (i.e., global acetylation of retinal histone H3) have been demonstrated to play an important role in the progression of diabetic retinopathy.

Additionally, omics analysis provides important information that enables the development of new treatment modalities in vascular eye disorders (diabetic retinopathy and neovascular age-related macular degeneration). Potential topics include, but are not limited to:

• Candidate genes for diabetic retinopathy (review)
• Epigenetic mechanisms and development of diabetic retinopathy (review)
• Proteomics and vascular ocular diseases
• Bioinformatics and new drug discoveries for vascular eye disorders
• New therapies (i.e., siRNA) and neovascular age-related macular degeneration (review)

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