BioMed Research International

Optimal Use of Biomarkers in Oncology


Publishing date
13 Mar 2015
Status
Published
Submission deadline
24 Oct 2014

Lead Editor

1Charles University in Prague, Prague, Czech Republic

2Hebrew University, Jerusalem, Israel

3Clinical Consultants Inc., Ridgewood, USA


Optimal Use of Biomarkers in Oncology

Description

The use of biomarkers in oncology has been much more extensive than in other diseases for more than 30 years. Their use has evolved beyond the research laboratory to more routine clinical use as in diagnosis, monitoring of disease status, and treatment efficacy.

With the advances in molecular biology, other biomarkers than the "classical" serum markers are being developed for clinical use: gene mutations, microRNA, circulating tumor cells, circulating DNA, and others currently in research. Biomarkers such as these are currently being used for prediction potential “at risk” for disease as well as response to therapy (predictive biomarkers) and for disease prognosis (prognostic biomarkers).

In oncological routine, the correlation of biomarker levels with the clinical status and medical imaging methods is of great significance. The purpose of the correlation is twofold: providing a sequential and/or more specific diagnostics and keeping these procedures within affordable economical limits.

We invite research scientists and other investigators to contribute original research articles as well as review articles that address the optimal use of biomarkers in oncology.

Potential topics include, but are not limited to:

  • Biomarkers measurement and their impact on the disease state (diagnostics and followup)
  • Circulation tumor cells and circulation tumor DNA as prognostic and predictive markers
  • MicroRNA as prognostic markers in cancer
  • Molecular markers to predict clinical outcome and toxicity in cancer
  • Biomarkers for the selection of therapy, prediction, and monitoring
  • Genetics and biomarkers in personalization of cancer treatment
  • Correlation of biomarkers and medical imaging
  • Perspectives on the use of biomarkers in oncology

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 423159
  • - Editorial

Optimal Use of Biomarkers in Oncology

Marie Karlikova | Ondrej Topolcan | ... | Tomas Zima
  • Special Issue
  • - Volume 2015
  • - Article ID 475920
  • - Review Article

Potential Utility of Novel Biomarkers in Active Surveillance of Low-Risk Prostate Cancer

Jeong Hyun Kim | Sung Kyu Hong
  • Special Issue
  • - Volume 2015
  • - Article ID 345219
  • - Review Article

Gamma-Glutamylcyclotransferase: A Novel Target Molecule for Cancer Diagnosis and Treatment

Susumu Kageyama | Eiki Hanada | ... | Akihiro Kawauchi
  • Special Issue
  • - Volume 2015
  • - Article ID 341042
  • - Research Article

Prognostic Value of MRS Metabolites in Postoperative Irradiated High Grade Gliomas

Maria Tolia | Dimitrios Verganelakis | ... | Vasileios Kouloulias
  • Special Issue
  • - Volume 2015
  • - Article ID 824514
  • - Review Article

Cytoglobin as a Biomarker in Cancer: Potential Perspective for Diagnosis and Management

Tatsha C. Bholah | Vidushi S. Neergheen-Bhujun | ... | Theeshan Bahorun
  • Special Issue
  • - Volume 2015
  • - Article ID 986024
  • - Clinical Study

Concordance of Hypermethylated DNA and the Tumor Markers CA 15-3, CEA, and TPA in Serum during Monitoring of Patients with Advanced Breast Cancer

Søren Kristiansen | Lars Mønster Jørgensen | ... | György Sölétormos
  • Special Issue
  • - Volume 2015
  • - Article ID 485732
  • - Research Article

Prognostic Significance of Serum Inflammatory Response Markers in Newly Diagnosed Non-Small Cell Lung Cancer before Chemoirradiation

Maria Tolia | Nikolaos Tsoukalas | ... | Vassilis Kouloulias
  • Special Issue
  • - Volume 2015
  • - Article ID 896432
  • - Review Article

hERG1 Potassium Channels: Novel Biomarkers in Human Solid Cancers

Elena Lastraioli | Tiziano Lottini | ... | Annarosa Arcangeli
  • Special Issue
  • - Volume 2015
  • - Article ID 792187
  • - Review Article

B-Cell Activating Factor as a Cancer Biomarker and Its Implications in Cancer-Related Cachexia

Michal Rihacek | Julie Bienertova-Vasku | ... | Lenka Zdrazilova-Dubska
  • Special Issue
  • - Volume 2015
  • - Article ID 914740
  • - Research Article

The Application of Classification and Regression Trees for the Triage of Women for Referral to Colposcopy and the Estimation of Risk for Cervical Intraepithelial Neoplasia: A Study Based on 1625 Cases with Incomplete Data from Molecular Tests

Abraham Pouliakis | Efrossyni Karakitsou | ... | Petros Karakitsos
BioMed Research International
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Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore4.100
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