Looking at the rise in infections caused by different multi-drug resistant (MDR) bacteria, it is essential to elucidate the basic mechanism of antibiotic resistance to discover effective methods for diagnosis and treatment of infections. It will help the scientific community to determine novel protein drug targets which can be manipulated further for drug discovery. Due to the unselective use of antibiotics in the present pandemic, drug-resistant strains could develop which can be a threat in the future for mankind.

This Special Issue aims to integrate the previous and current knowledge in the field of antibiotic resistance right from diagnosis, pathophysiology, and novel therapeutics. This Special Issue will welcome original research and reviews focusing on the detailed mechanism of bacterial infection, pathogenesis, and control. Furthermore, it will also provide knowledge regarding current strategies for the diagnosis of major MDR bacteria and its treatment options. Specific topics such as, quantification of pathogenic bacteria, high-resolution melting analysis techniques, biosynthesis pathways, and rational structure-based drug design for MDR in bacterial infection would be welcomed from authors who have significant contributions and quality publications in their proposed area.

Potential topics include but are not limited to the following:

• State-of-the-art techniques for the diagnosis of MDR infections
• Search for novel drug targets for the treatment of MDR infections
• Pathogenesis and infection control of MDR pathogens
• Mechanistic perspectives of host-pathogen interaction
• Structure-aided drug development for the control of MDR infections
• Impact of COVID 19 outbreak on antibiotic resistance