BioMed Research International

Upstream and Downstream of Recombinants Biomolecules to Health Care Industry


Status
Published

1University of Campinas, Campinas, Brazil

2Universidade do Minho, Braga, Portugal

3São Paulo State University (UNESP), Araraquara, Brazil

4Universidad de La Frontera, Temuco, Chile


Upstream and Downstream of Recombinants Biomolecules to Health Care Industry

Description

Biotechnology processes are the only economically viable solution for the production of some pharmaceutical active principles. This special issue aims to report the last developments on downstream and upstream of biopharmaceuticals.

Developments in molecular biology, recombinant techniques, separation, and purification methods lead the way for innovative and economical forms of production of active principles for pharmacology by biotechnology processes.

Potential topics include, but are not limited to:

  • Industrial biopharmaceutical and biotechnology
  • Separation and purification technologies
  • Bioprocesses optimization
  • Biotransformations
  • Formulations for cosmetic/topical/dermatological applications
  • Scale-up and modelling of bioprocess

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 9374847
  • - Editorial

Upstream and Downstream of Recombinants Biomolecules to Health Care Industry

Priscila G. Mazzola | Arthur Cavaco-Paulo | ... | Jorge F. B. Pereira
  • Special Issue
  • - Volume 2016
  • - Article ID 5683026
  • - Research Article

Full-Length cDNA, Prokaryotic Expression, and Antimicrobial Activity of UuHb-F-I from Urechis unicinctus

Rongli Niu | Xiang Chen
  • Special Issue
  • - Volume 2016
  • - Article ID 8356435
  • - Research Article

Mutation Detection in an Antibody-Producing Chinese Hamster Ovary Cell Line by Targeted RNA Sequencing

Siyan Zhang | Jason D. Hughes | ... | Shuangping Shi
  • Special Issue
  • - Volume 2016
  • - Article ID 3073949
  • - Research Article

Cloning and Expression of the γ-Polyglutamic Acid Synthetase Gene pgsBCA in Bacillus subtilis WB600

Biaosheng Lin | Zhijuan Li | ... | Maochun Luo
  • Special Issue
  • - Volume 2016
  • - Article ID 2074149
  • - Research Article

Improved Stability of a Model IgG3 by DoE-Based Evaluation of Buffer Formulations

Brittany K. Chavez | Cyrus D. Agarabi | ... | Kurt A. Brorson
  • Special Issue
  • - Volume 2016
  • - Article ID 8409183
  • - Research Article

Azocasein Substrate for Determination of Proteolytic Activity: Reexamining a Traditional Method Using Bromelain Samples

Diego F. Coêlho | Thais Peron Saturnino | ... | Elias Basile Tambourgi
  • Special Issue
  • - Volume 2015
  • - Article ID 636249
  • - Research Article

Enhanced and Secretory Expression of Human Granulocyte Colony Stimulating Factor by Bacillus subtilis SCK6

Shaista Bashir | Saima Sadaf | ... | Muhammad Waheed Akhtar
  • Special Issue
  • - Volume 2015
  • - Article ID 703213
  • - Research Article

One-Step Recovery of scFv Clones from High-Throughput Sequencing-Based Screening of Phage Display Libraries Challenged to Cells Expressing Native Claudin-1

Emanuele Sasso | Rolando Paciello | ... | Nicola Zambrano
BioMed Research International
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Acceptance rate8%
Submission to final decision110 days
Acceptance to publication24 days
CiteScore5.300
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