BioMed Research International

Natural Compounds against Cancer, Inflammation, and Oxidative Stress


Publishing date
01 Feb 2019
Status
Published
Submission deadline
14 Sep 2018

1"Campus Bio-Medico" University, Rome, Italy

2Istituto Superiore di Sanità, Rome, Italy

3University of Rome “Tor Vergata”, Rome, Italy

4Augusta University, Augusta, USA


Natural Compounds against Cancer, Inflammation, and Oxidative Stress

Description

Natural products, compounds derived from animals, microorganisms, and, especially, plants, have been used in prevention and treatment of various human diseases for thousands of years. Some of these bioactive compounds with beneficial effects on human health are contained also in common foods and beverages. In recent years, the interest in the use of natural compounds and their derivatives has been renewed, even for the discovery and development of new drugs or for repurposing of the old ones.

Natural products, in particular, phytochemicals, have been extensively studied for their anticancer activities, through the potential modulation of cancer initiation and growth, cellular differentiation, apoptosis and autophagy, angiogenesis, and metastatic dissemination. Moreover, a considerable number of studies reported the use of natural compounds for their anti-inflammatory activity, since inflammation is considered the basis of various disease conditions, including cancer. The use of herbal preparation in combination with suitable diet represents also one of the most promising strategies to treat metabolic disorders (diabetes, obesity, metabolic syndrome, and so on). Furthermore, due to their several biological activities, natural compounds represent good candidates for preventing and even curing the effects of neurodegenerative diseases.

We invite researchers to contribute to this special issue with original research articles as well as review articles that will aim to highlight recent advances on the role of natural compounds and natural-derived drugs in counteracting many human diseases. Articles regarding the anticancer activity of phytochemicals are particularly encouraged.

Potential topics include but are not limited to the following:

  • The use of natural compounds as anticancer and anti-inflammatory agents
  • Impact of natural compounds, especially phytochemicals or nutraceuticals, against human inflammation-related and oxidative stress-related diseases
  • Characterization of herbal extracts with anticancer and immunomodulatory activities
  • Role of natural products in oxidative stress associated with acute and chronic diseases
  • Epigenetic changes induced by natural molecules
  • Clinical studies on protective role of natural bioactive agents under oxidative stress and inflammation conditions
  • Effects of nutrition and diet on human diseases
  • Phytochemicals and age-related diseases, including ocular inflammatory ones
  • Effects of natural compounds on metabolic and neurological disorders
  • Antioxidants and angiogenesis

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 9495628
  • - Editorial

Natural Compounds against Cancer, Inflammation, and Oxidative Stress

Claudio Tabolacci | Cinzia Forni | ... | Francesco Facchiano
  • Special Issue
  • - Volume 2019
  • - Article ID 3548396
  • - Research Article

Effect of Immunomodulatory Supplements Based on Echinacea Angustifolia and Echinacea Purpurea on the Posttreatment Relapse Incidence of Genital Condylomatosis: A Prospective Randomized Study

Nicoletta De Rosa | Pierluigi Giampaolino | ... | Giuseppe Bifulco
  • Special Issue
  • - Volume 2019
  • - Article ID 8748253
  • - Review Article

Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases

Cinzia Forni | Francesco Facchiano | ... | Ravirajsinh N. Jadeja
  • Special Issue
  • - Volume 2019
  • - Article ID 7213913
  • - Research Article

Diosgenin and Its Fenugreek Based Biological Matrix Affect Insulin Resistance and Anabolic Hormones in a Rat Based Insulin Resistance Model

Rita Kiss | Georgina Pesti-Asbóth | ... | Judit Remenyik
  • Special Issue
  • - Volume 2019
  • - Article ID 8361858
  • - Research Article

Selectivity of Dietary Phenolics for Inhibition of Human Monoamine Oxidases A and B

Zhenxian Zhang | Hiroki Hamada | Phillip M. Gerk
  • Special Issue
  • - Volume 2019
  • - Article ID 6146972
  • - Research Article

Effect of Chemotherapeutics and Tocopherols on MCF-7 Breast Adenocarcinoma and KGN Ovarian Carcinoma Cell Lines In Vitro

Daniela Figueroa | Mohammad Asaduzzaman | Fiona Young
  • Special Issue
  • - Volume 2019
  • - Article ID 2462561
  • - Research Article

The Effects of Korea Red Ginseng on Inflammatory Cytokines and Apoptosis in Rat Model with Chronic Nonbacterial Prostatitis

Sang Wook Kang | Je-Hoon Park | ... | Su Kang Kim
  • Special Issue
  • - Volume 2019
  • - Article ID 1970878
  • - Clinical Study

Effects of a New Combination of Medical Food on Endothelial Function and Lipid Profile in Dyslipidemic Subjects: A Pilot Randomized Trial

Francesco Landi | Anna Maria Martone | ... | Angelo Santoliquido
  • Special Issue
  • - Volume 2018
  • - Article ID 6137420
  • - Research Article

Natural Compound Oridonin Inhibits Endotoxin-Induced Inflammatory Response of Activated Hepatic Stellate Cells

Claire B. Cummins | Xiaofu Wang | ... | Ravi S. Radhakrishnan
  • Special Issue
  • - Volume 2018
  • - Article ID 3120972
  • - Research Article

Degalactotigonin, a Steroidal Glycoside from Solanum nigrum, Induces Apoptosis and Cell Cycle Arrest via Inhibiting the EGFR Signaling Pathways in Pancreatic Cancer Cells

Hoang Le Tuan Anh | Phuong Thao Tran | ... | Jeong-Hyung Lee
BioMed Research International
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Acceptance rate31%
Submission to final decision81 days
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CiteScore2.410
Impact Factor2.197
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