BioMed Research International

Neurobiology of Hearing Loss and Ear Disease


Status
Published

Lead Editor

1Chungnam National University, Daejeon, Republic of Korea

2University of California, Los Angeles, Los Angeles, USA

3University of Texas Southwestern Medical Center, Dallas, USA

4University of California, Davis, Davis, USA


Neurobiology of Hearing Loss and Ear Disease

Description

Hearing loss is a worldwide health problem. It is usually irreversible, since the hair cells in the auditory epithelium cannot regenerate. With the advancement of molecular biology and techniques, recent researches for hearing loss are focused on innovative approaches such as gene therapy and stem cell therapy.

Numerous studies were performed to understand the pathophysiology and to develop possible therapeutic approaches for hearing loss. Still, these processes were not quite effective. One of the reasons for this is the location of cochlea. Compared to the other sensory organs, delivering the therapeutic agent to the cochlea especially organ of Corti is not feasible so far. Therefore, development of noninvasive and effective delivery technique will be another promising research subject.

Another interesting subject is plastic change of central nervous system. It is well known that brain changes its structure and functions to adjust itself to the external stimuli. Likewise, loss of external acoustic input could result in changes of auditory cortex and pathway. After this plastic change, therapeutic efficiency of hearing rehabilitation devices might be different. Therefore, understanding the change of auditory cortex and brainstem pathway after the deafness is very important.

As described above, hearing researches can be innovative and challenging and some are very closely related to plastic change of nervous structures. In this special issue, we invite investigators to contribute original research articles as well as review articles that will help us better understand the neurobiology of hearing loss.

Potential topics include but are not limited to the following:

  • Molecular mechanism of hearing loss
  • Advances in hearing loss research
  • Brain plasticity in hearing loss
  • Genetic hearing loss
  • Age-related hearing loss
  • Hearing loss associated with systemic disease
  • Relations of hearing loss with other neurologic diseases
  • Drug delivery to the cochlea
  • Gene therapy for hearing loss
  • Stem cells therapy for hearing loss
  • Molecular mechanism of otitis media
  • Tinnitus and brainstem
  • Sciences of cochlear implant and hearing aid

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 2464251
  • - Editorial

Neurobiology of Hearing Loss and Ear Disease

Yong-Ho Park | Sung K. Moon | ... | Jeong-Han Lee
  • Special Issue
  • - Volume 2018
  • - Article ID 7807426
  • - Research Article

Effect of Long-Term Sodium Salicylate Administration on Learning, Memory, and Neurogenesis in the Rat Hippocampus

Haichen Niu | Sheng Ding | ... | Qiang Zhang
  • Special Issue
  • - Volume 2018
  • - Article ID 6387983
  • - Research Article

Effect of Formaldehyde on Human Middle Ear Epithelial Cells

Shin Hye Kim | Ji-Woong Choi | ... | Moo Kyun Park
  • Special Issue
  • - Volume 2018
  • - Article ID 5675848
  • - Research Article

Does the Width of the Bony Cochlear Nerve Canal Predict the Outcomes of Cochlear Implantation?

Juyong Chung | Jeong Hun Jang | ... | Seung-Ha Oh
  • Special Issue
  • - Volume 2018
  • - Article ID 5058729
  • - Research Article

Effect of Lead on Human Middle Ear Epithelial Cells

Shin Hye Kim | Sun Hwa Shin | ... | Jae-Jun Song
  • Special Issue
  • - Volume 2018
  • - Article ID 9158187
  • - Research Article

Secondary Degeneration of Auditory Neurons after Topical Aminoglycoside Administration in a Gerbil Model

Jae-Hun Lee | Min Young Lee | ... | Jae Yun Jung
  • Special Issue
  • - Volume 2018
  • - Article ID 6280969
  • - Research Article

Transient Abnormalities in Masking Tuning Curve in Early Progressive Hearing Loss Mouse Model

Marion Souchal | Ludimila Labanca | ... | Fabrice Giraudet
  • Special Issue
  • - Volume 2018
  • - Article ID 7601232
  • - Research Article

Susceptibility of Diabetic Mice to Noise Trauma

Wook Kyoung Han | Eung Hyub Kim | ... | Yong-Ho Park
  • Special Issue
  • - Volume 2018
  • - Article ID 6795397
  • - Research Article

Evaluation of Cerebral White Matter in Prelingually Deaf Children Using Diffusion Tensor Imaging

Kye Hoon Park | Won-Ho Chung | ... | Jong-Min Lee
  • Special Issue
  • - Volume 2017
  • - Article ID 4630241
  • - Research Article

A Simple Model for Inducing Optimal Increase of SDF-1 with Aminoglycoside Ototoxicity

Hyun Mi Ju | Sun Hee Lee | ... | Young Joon Seo
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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