BioMed Research International

Applications of Computational Methods for Prediction, Prevention, Diagnosis, and Treatment of Neurodegenerative Diseases 2021


Publishing date
01 Dec 2022
Status
Published
Submission deadline
15 Jul 2022

Lead Editor

1Jiangsu University, Zhenjiang, China

2Harvard Medical School, Boston, USA

3Geneis Beijing, Beijing, China


Applications of Computational Methods for Prediction, Prevention, Diagnosis, and Treatment of Neurodegenerative Diseases 2021

Description

Neurodegenerative disorders, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Amyotrophic lateral sclerosis (ALS), are formidable clinical illnesses whose diagnosis, treatment, and prognosis are complex. As a result, no effective treatment for AD has been found so far. There is plenty of evidence to suggest that computational methods, especially those in bioinformatics and medical informatics, could be critical in solving this issue.

In the post-genome era, numerous computational methods have been developed and applied to the neurological field. Accurate prediction and diagnosis is a pivotal goal to prevent the onset of neurodegenerative diseases. With the assistance of biomarkers identified by computational methods, neurologists are able to diagnose the disease at its early stage. Based on next-generation sequencing (NGS) technologies, the risk gene loci and proteins can be detected. Accompanied by Magnetic Resonance Imaging (MRI) technology, clinicians can improve or assure their diagnosis and classification of neurodegenerative disorders. Furthermore, appropriate bioinformatics tools can help biologists to explore the aetiology of neurodegenerative diseases, which may shed light on the underlying mechanisms of brain impairment. In addition, some biomarkers can be utilized to promote drug repurposing as well as de novo drug design. Finally, wet-lab experiments can also be developed that are compatible with computational methods for further validation.

This Special Issue welcomes investigators to contribute original research and review articles related to computational methods and tools for diagnosis, treatment, prognosis, and prevention of neurodegenerative disorders.

Potential topics include but are not limited to the following:

  • Algorithms, methods, and tools for diagnosis, treatment, prognosis, and prevention of neurodegenerative disorders
  • Machine learning or deep learning methods on dimensional reduction and feature selection for big noisy data in neurodegenerative disorders
  • Bioinformatics methods in identifying disease mechanisms of neurodegenerative disorders
  • Methods integrating medical images and sequencing data in neurodegenerative disorders
  • Drug repositioning and drug target prediction for neurodegenerative disorders
  • Validation of results from computational studies by wet-lab experiments
  • Clinical applications of computational studies in neurodegenerative disorders

Articles

  • Special Issue
  • - Volume 2024
  • - Article ID 9785756
  • - Retraction

Retracted: Clinical Value of sTREM-1, PCT, and 1,3-β-D Glucan in Diagnosis of Immune-Associated Pulmonary Interstitial Disease with Fungal Infection

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9765786
  • - Retraction

Retracted: Analysis on the Efficacy of Bronchial Artery Chemoembolization Combined with 125I Seed Implantation in the Therapy of Advanced Non-Small-Cell Lung Cancer Based on the Medical Database

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9876769
  • - Retraction

Retracted: Value of Transabdominal Combined Transvaginal Color Doppler Ultrasonography in the Distinguish between Uterine Adenomyoma and Uterine Fibroids

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9896369
  • - Retraction

Retracted: circSOX4 Enhances Hepatocellular Carcinoma Progression via miR-218-5p/YY1 Signaling

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9867437
  • - Retraction

Retracted: Effect of Warming Yang, Tonifying Kidney, and Removing Arthralgia Therapy on Cold-Dampness Arthralgia Type Ankylosing Spondylitis and Its Influence on the Levels of Humoral Factor in Human Serum

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9826758
  • - Retraction

Retracted: Study on Psychological Stress Response and Intervention Countermeasures of Exposed Population under Sudden Public Health Crisis

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9823789
  • - Retraction

Retracted: C-myc/TSPEAR-AS2 Axis Facilitates Breast Cancer Growth and Metastasis in a GLUT1-Dependent Glycolysis Manner

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9816426
  • - Retraction

Retracted: Mitochondrial-Targeted Antioxidant Peptide SS31 Prevents RPE Cell Death under Oxidative Stress

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9847302
  • - Retraction

Retracted: Association between Perceived Salt Intake and Arterial Stiffness

BioMed Research International
  • Special Issue
  • - Volume 2023
  • - Article ID 9891802
  • - Retraction

Retracted: Effects of Different Ovulation Induction Regimens on Sex Hormone Levels and Serum CTRP3 and CTRP15 Levels in Patients with Polycystic Ovary Syndrome (PCOS)

BioMed Research International
BioMed Research International
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Acceptance rate8%
Submission to final decision128 days
Acceptance to publication21 days
CiteScore5.300
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