BioMed Research International

Challenges for Diagnosis of Malaria and Neglected Tropical Diseases in Elimination Settings

Publishing date
31 Jul 2015
Submission deadline
13 Mar 2015

Lead Editor

1Walter and Eliza Hall Institute of Medical Research, Parkville, Australia

2University of Queensland, Brisbane, Australia

3Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Brazil

4Instituto de Ciencia de Materiales de Madrid Sor Juana Inés de la Cruz, Madrid, Spain

5University of Western Australia, Perth, Australia

6Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea

Challenges for Diagnosis of Malaria and Neglected Tropical Diseases in Elimination Settings


Malaria and several of the neglected tropical diseases (NTDs) such as schistosomiasis and lymphatic filariasis are either in decline, currently scheduled for elimination, or already eliminated from various areas.

Amongst the many challenges associated with achieving and sustaining elimination status, the limitation of diagnostic tests to detect these diseases may well prove to be one of the most crucial.

Field-applicable malaria diagnostic tests detect only about half of the symptomatic infections and a much lower proportion of asymptomatic infections which may contribute significantly to disease transmission. The situation is similarly complex for NTDs such as schistosomiasis, soil transmitted helminthiases, and others, where novel more sensitive methods for detection have not yet reached the required stages of maturity.

We invite authors to submit original research and review articles illustrating challenges to malaria and the WHO-listed NTDs, which are listed at

Field based evaluation of novel and/or currently employed diagnostic methods especially for mass surveillance and/or surveillance of risk or indicator groups

Potential topics include, but are not limited to:

  • Studies describing malaria or NTD surveillance in areas of very low endemicity, specifically strategies to detect asymptomatic infections
  • Basic and applied research aiming to develop novel diagnostic techniques for malaria and the NTDs
  • Mathematical modelling studies, for example, illustrating the effect of improved diagnostic capability on our ability to control these diseases
  • Studies describing disease resurgence or failed elimination events
  • Studies that differentiate between challenges for diagnosis of different pathogen species (e.g., P. falciparum versus P. vivax and Schistosoma haematobium versus S. mansoni/japonicum)


  • Special Issue
  • - Volume 2015
  • - Article ID 270756
  • - Editorial

Challenges for Diagnosis of Malaria and Neglected Tropical Diseases in Elimination Settings

Stephan Karl | Malcolm K. Jones | ... | Marcus Lacerda
  • Special Issue
  • - Volume 2015
  • - Article ID 834371
  • - Review Article

Diagnostic Options and Challenges for Dengue and Chikungunya Viruses

Stacey K. Mardekian | Amity L. Roberts
  • Special Issue
  • - Volume 2015
  • - Article ID 867846
  • - Research Article

Loop Mediated Isothermal Amplification for Detection of Trypanosoma brucei gambiense in Urine and Saliva Samples in Nonhuman Primate Model

Maina Ngotho | John Maina Kagira | ... | Naomi Wangari Maina
  • Special Issue
  • - Volume 2015
  • - Article ID 135689
  • - Research Article

Comparative Study of the Accuracy of Different Techniques for the Laboratory Diagnosis of Schistosomiasis Mansoni in Areas of Low Endemicity in Barra Mansa City, Rio de Janeiro State, Brazil

Maria Cristina Carvalho Espírito-Santo | Mónica Viviana Alvarado-Mora | ... | Ronaldo Cesar Borges Gryschek
  • Special Issue
  • - Volume 2015
  • - Article ID 428205
  • - Review Article

Serological Diagnosis and Follow-Up of Human Cystic Echinococcosis: A New Hope for the Future?

Raúl Manzano-Román | Carlos Sánchez-Ovejero | ... | Mar Siles-Lucas
  • Special Issue
  • - Volume 2015
  • - Article ID 583262
  • - Review Article

Overview of the Diagnostic Methods Used in the Field for Human African Trypanosomiasis: What Could Change in the Next Years?

Julien Bonnet | Clotilde Boudot | Bertrand Courtioux
BioMed Research International
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