BioMed Research International

Integrated Analysis of Multiscale Large-Scale Biological Data for Investigating Human Disease 2020


Publishing date
01 Dec 2020
Status
Closed
Submission deadline
24 Jul 2020

Lead Editor

1Shanghai Institutes for Biological Sciences - Chinese Academy of Sciences, Shanghai, China

2Shanghai Maritime University, Shanghai, China

3Monash University, Victoria, Australia

4Shanghai Institute of Materia Medica - Chinese Academy of Sciences, Shanghai, China

5Geneis (Beijing) Co. Ltd, Beijing, China

6Zymo Research Corp, California, USA

This issue is now closed for submissions.
More articles will be published in the near future.

Integrated Analysis of Multiscale Large-Scale Biological Data for Investigating Human Disease 2020

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Integrating large-scale data obtained at multiscales is essential for understanding the molecular basis of complex diseases and providing useful therapeutic targets. Several large projects, such as The Cancer Genome Atlas (TCGA), Cancer Cell Line Encyclopedia (CCLE), Genotype-Tissue Expression (GTEx), and Molecular Taxonomy of Breast Cancer International Consortium (METABRIC), have measured the somatic mutation, copy number variation (CNV), mRNA expression, microRNA expression, and methylation data and made them publicly available. Recently, many statistical methods and analysis tools have been developed based on these multiscale large-scale data.

The aim of this Special Issue is to collate original research and review articles from oncologists, computational biologists, mathematical biologists, bioinformaticians, systems biologists, and computational pharmacists with a focus on these statistical methods and analysis tools.

Potential topics include but are not limited to the following:

  • Subtype stratification of patients
  • Multiscale network construction
  • Network module identification
  • Predictive model of disease state
  • Biomarker discovery
  • Combinatorial drug discovery
  • Translational medicine
  • Novel computational methods in large biology data analysis
  • Inferring gene function from expression data
  • Inferring gene function from genome sequence data
  • Integrating expression data with other genome-wide data for functional annotation
  • Integrating expression data from different organisms

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 6248686
  • - Research Article

PmDNE: Prediction of miRNA-Disease Association Based on Network Embedding and Network Similarity Analysis

Junyi Li | Ying Liu | ... | Yadong Wang
  • Special Issue
  • - Volume 2020
  • - Article ID 1971324
  • - Research Article

Optimizing the Catheter Care and Maintenance Strategy of Short-Term Catheterization among Hospitalized Patients in Microbiological Approach

Xiaoqiong Peng | Wei Qian | ... | Jiangang Hou
  • Special Issue
  • - Volume 2020
  • - Article ID 8579651
  • - Research Article

Identification of Long Noncoding RNA Biomarkers for Hepatocellular Carcinoma Using Single-Sample Networks

Xiaoqing Yu | Jingsong Zhang | ... | Chun Li
  • Special Issue
  • - Volume 2020
  • - Article ID 3620425
  • - Research Article

Application Value of SAT-TB Combined with Acid-Fast Staining in the Diagnosis and Treatment of Pulmonary Tuberculosis

Chaochao Qiu | Ning Pan | ... | Jichan Shi
  • Special Issue
  • - Volume 2020
  • - Article ID 3909416
  • - Research Article

Recognition of Immune Microenvironment Landscape and Immune-Related Prognostic Genes in Breast Cancer

Huiling Wang | Shuo You | ... | Qian Fang
  • Special Issue
  • - Volume 2020
  • - Article ID 9124792
  • - Research Article

A Recurrence-Specific Gene-Based Prognosis Prediction Model for Lung Adenocarcinoma through Machine Learning Algorithm

Shaohua Xu | Jie Zhou | ... | Zhengfu He
  • Special Issue
  • - Volume 2020
  • - Article ID 4965670
  • - Research Article

Studying the Role and Molecular Mechanisms of MAP4K3 in Sorafenib Resistance of Hepatocellular Carcinoma

Yi Shi | Xiaofei Mo | ... | Gang Chen
  • Special Issue
  • - Volume 2020
  • - Article ID 9471329
  • - Research Article

Analysis on the Expression and Prognostic Value of LncRNA FAF in Patients with Coronary Heart Disease

Hai Xu | Xiwen Zhang | ... | Yicheng Jiang
  • Special Issue
  • - Volume 2020
  • - Article ID 2148706
  • - Research Article

HO-1/PINK1 Regulated Mitochondrial Fusion/Fission to Inhibit Pyroptosis and Attenuate Septic Acute Kidney Injury

Hai-Bo Li | Xi-Zhe Zhang | ... | Jian-Bo Yu
  • Special Issue
  • - Volume 2020
  • - Article ID 8513860
  • - Research Article

A Computational Framework to Study the Effect of Acupuncture on Obesity by Integrating Multiple Levels of Data

Huihui Liu | Mingjun Liu | ... | Jinming Chen
BioMed Research International
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Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.