In recent years, frontiers of research in science, medicine, and modern dentistry have been driven by developments in materials science, biomedical engineering, nanomedicine and biology, biotechnology, nanotechnology and nanorobotics, and nanoelectronics. Biomaterials serve a main role in the engineering of functional tissue replacements, supporting cell adhesion, vehicles for cell transplantation, and systems for controlled drug delivery. Advanced biomaterials inspired by biological systems and processes are likely to influence the development of novel technologies for a wide variety of applications.

The development of new biocompatible materials and/or improvement of current material characteristics are expected to broaden the diversity of applications of biomaterials in dentistry field in upcoming years. The progress in materials research including dentin bonding, impression materials, luting cements, glass ionomers, glass carbomers, composites, and ceramics requires an improved understanding in multidisciplinary approach, as well as the development of new design methodologies in order to reach better properties in biologic performance and better biocompatibility. The objectives of all these biomaterials and technologies are not only to replace missing or damaged tooth tissues, but also now to promote tissue regeneration and also prevent healthy tooth tissue.

Comprehension of recent advances in biomaterial of dentistry would lead to appropriate applications of these biomaterials in clinical cases and successful strategies to improve dental treatment outcomes to better serve patients. It is important to choose most appropriate material for the regeneration of the tooth structure via biomimetic processes. In other words, choosing the appropriate dental material and its successful clinical use directly affect treatment outcome and long term results.

For this purpose, we invite investigators to submit original research articles, clinical studies, and review articles that will help to understand the development and application of biomaterials in dentistry. We are specifically interested in articles describing current research trends as well as future perspectives.

Potential topics include, but are not limited to:

• New biomaterials and biotechnologies in dentistry
• Nanomaterials, nanorobotics, and their applications
• Resin based materials in dentistry
• Fatigue behavior of restorative dental materials
• The synthesis of novel scaffolds
• Techniques to characterize material performance
• New technologies and strategies in dental tissue regeneration and bioengineering
• New approaches in adhesion
• Definitions and applications of the mechanical and physical properties of dental biomaterials
• Concepts of biocompatibility
• Biomimetic approach in dentistry