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Genetic Control of Immune Response and Susceptibility to Infectious Diseases

Call for Papers

Susceptibility to and control of infectious diseases are multifactorial, dynamic, and phenotypically diverse. Both genetic and nongenetic variables can influence them. Knowledge about roles of genetic variations seen in host immune response genes comes mainly from population genetics of candidate genes through interindividual susceptibility association studies. The observed interindividual variation is due, in part, to risk-modifying polymorphisms (rare and common) in agonist and antagonist genes of the innate and adaptive immune responses. The mechanisms that underlie the observed interindividual variation in control/resistance/susceptibility are not completely understood. We invite investigators to contribute original research articles as well as review articles that will advance the knowledge and stimulate research efforts to understand the basis of genetic control of immune response and susceptibility to infectious diseases. Potential topics include, but are not limited to:

  • Variant discovery and validation through conventional genetic analyses or systems biology approaches
  • Role of genetic variants: phenotype, function, and expression profiling
  • Application of genetic markers in biotechnology and diagnostics
  • Announcement of new or replica population studies data on genetic parameters

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

Manuscript DueFriday, 1 March 2013
First Round of ReviewsFriday, 24 May 2013
Publication DateFriday, 19 July 2013

Lead Guest Editor

  • Enrique Medina-Acosta, Department of Biotechnology, Center for Biosciences and Biotechnology, State University of Norte Fluminense, Campos dos Goytacazes, RJ, Brazil

Guest Editors

  • Helder I Nakaya, Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA
  • Regina Célia de Souza Campos Fernandes, Departamento de Pediatria, Faculdade de Medicina de Campos, Hospital Escola Ávaro Alvim, Campos Dos Goytacazes, RJ, Brazil
  • Alessandra Pontillo, Laboratory of Medical Research in Dermatology and Immunodeficiency, School of Medicine, University of São Paulo, São Paulo, SP, Brazil