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Emerging Viral Diseases and New Challenges: Globalization, Climate Change, and Evolution

Call for Papers

Since the discovery of the viruses around 1890, virologists have tried to decipher the mechanisms through which these small organized molecular machines govern the different cellular processes. Although several progresses have been made during past 125 years, new challenges have currently arisen. Recent isolation of novel Giant viruses from Siberian permafrost indicates that global warming will likely increases the risk of viral emergence. Moreover, the development in the transport system has increased the global-trade, and it has in turn facilitated the spread of emerging viruses Likewise, the emergence of avian influenza virus H5N1 in 2005 or the pandemic influenza virus H1N1p/2009 indicated that animal-to-human transmission occurred during the handling of livestock animals. Viral emergence also occurred as a result of the selection against antivirals. Growing reports of antiviral resistance (e.g., human immunodeficiency virus, influenza virus, or hepatitis B virus) are an important alert in the public health. Finally, it is also important to get deep insight into viral evolutionary mechanisms for the emergence. A few examples include the outbreaks of the Middle East Respiratory Syndrome Corona Virus (MERS-CoV), outbreaks of Zika virus (ZIKV) in the Pacific Islands and Latin America, and the reemergence of human norovirus (NoV).

For this reason, the aim of the special issue is to publish original research articles as well as reviews focused on the impact of climate change, human development, and globalization on the emergence, epidemiology, and change in the evolutionary patterns of emerging viral diseases.

Potential topics include but are not limited to the following:

  • Studies of biological and molecular characterization of newly emerging viruses with emphasis on Zika virus, Coronavirus, and influenza virus
  • Novel pathological mechanisms of emerging viruses specifically those linked to novel climate conditions, human development, and globalization including host-jumping events, variation in tropism, and virulence
  • Evolutionary mechanisms of the viral agents using the state-of-the-art methodologies (e.g., phylodynamic or phylogeographic approaches, analyses of quasispecies composition, and viral host coevolution)
  • The impact of the climate change on epidemiology of viral agents (e.g., West Nile virus, Dengue Virus, Chikungunya, and Bluetongue virus) with emphasis on those showing new pattern of geographical spread
  • Report of new emerging viral disease including the emergence of new species, linages or viral strains, with emphasis on those that have emerged as consequence of the human development and globalization, for example, new lineages which have emerged as escaping variants as a result of vaccination or the introduction of susceptible host animal species

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 23 March 2018
Publication DateAugust 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

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