BioMed Research International

Roles and Clinical Applications of Biomarkers in Cardiovascular Disease 2017


Lead Editor

1Magna Græcia University of Catanzaro, Catanzaro, Italy

2Interuniversity Center of Phlebolymphology (CIFL), Catanzaro, Italy

3University of Picardie Jules Verne, Amiens, France

Roles and Clinical Applications of Biomarkers in Cardiovascular Disease 2017


Cardiovascular and peripheral vascular diseases (CVD and PVD) are the leading cause of morbidity and mortality in Western countries. Assessing the risk for these diseases is an important aspect in clinical decision making and setting a therapeutic strategy. Biomarkers may be useful to better identify high-risk individuals, to diagnose disease conditions promptly and accurately, and to effectively prognosticate and treat patients with disease, targeting also specific biological sites.

Advances in functional genomics, proteomics, metabolomics, and bioinformatics have allowed discovering several biomarkers that may be informative with regard to the various stages of CVD and PVD and its sequelae.

This special issue is intended to present and discuss breakthrough in biological and technological developments in biomarkers identification which are expected to revolutionize clinical research environments and healthcare in the area of CVD and PVD.

Potential topics include but are not limited to the following:

  • Biomarkers in hypertension
  • Biomarkers in coronary artery disease
  • Biomarkers in heart failure
  • Biomarkers in arterial aneurysms
  • Biomarkers in aortic disease and aortic dissection
  • Biomarkers in cerebrovascular disease
  • Imaging biomarkers in cardiovascular disease
  • Biomarkers in preventive cardiology
  • Biomarkers in acute and chronic venous disease
  • Biomarkers in chronic leg ulcers
  • Biomarkers and dialysis vascular access
  • Matrix metalloproteinases (MMPs) and endothelial dysfunction
  • A disintegrin and metalloproteinase (ADAM), CVD, and PVD
  • A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS), CVD, and PVD
  • Tissue inhibitors of metalloproteinases (TIMPs), CVD, and PVD
  • Neutrophil gelatinase-associated lipocalin (NGAL), CVD, and PVD
  • Single nucleotide polymorphisms (SNPs), CVD, and PVD
  • MicroRNAs in the pathophysiology of CVD and PVD
  • Genetic markers in complex multigenic cardiovascular disease
  • Cytokines, CVD, and PVD


  • Special Issue
  • - Volume 2017
  • - Article ID 3093589
  • - Editorial

Roles and Clinical Applications of Biomarkers in Cardiovascular Disease 2017

Raffaele Serra | Stefano de Franciscis | Laurent Metzinger
  • Special Issue
  • - Volume 2017
  • - Article ID 8153024
  • - Review Article

Potential Biological Markers of Atrial Fibrillation: A Chance to Prevent Cryptogenic Stroke

István Szegedi | László Szapáry | ... | László Csiba
  • Special Issue
  • - Volume 2017
  • - Article ID 9158572
  • - Review Article

The Management of Cardiovascular Risk through Epigenetic Biomarkers

Laurent Metzinger | Stefano de Franciscis | Raffaele Serra
  • Special Issue
  • - Volume 2017
  • - Article ID 6519704
  • - Research Article

Hypofibrinolytic State in Subjects with Type 2 Diabetes Mellitus Aggravated by the Metabolic Syndrome before Clinical Manifestations of Atherothrombotic Disease

Elsa Aburto-Mejía | David Santiago-Germán | ... | Irma Isordia-Salas
  • Special Issue
  • - Volume 2016
  • - Article ID 3823809
  • - Research Article

Clinic Predictive Factors for Insufficient Myocardial Reperfusion in ST-Segment Elevation Myocardial Infarction Patients Treated with Selective Aspiration Thrombectomy during Primary Percutaneous Coronary Intervention

Jinfan Tian | Yue Liu | ... | Shuzheng Lyu
  • Special Issue
  • - Volume 2016
  • - Article ID 9872945
  • - Research Article

High Systolic and Diastolic Blood Pressure Variability Is Correlated with the Occurrence of Peripheral Arterial Disease in the First Decade following a Diagnosis of Type 2 Diabetes Mellitus: A New Biomarker from Old Measurement

Chi-Hsiao Yeh | Hsiu-Chin Yu | ... | Shun-Ying Yin
  • Special Issue
  • - Volume 2016
  • - Article ID 3708905
  • - Research Article

Elevated Levels of Plasma Superoxide Dismutases 1 and 2 in Patients with Coronary Artery Disease

Ji-Ren Peng | Ting-Ting Lu | ... | Wei-Min Li
BioMed Research International
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