In the last decade, remarkable advancements have been made in the field of orthodontics. With the development of newer advances such as artificial intelligence, the use of robotics, auto-transplantation, newer drugs, and genetics in clinical practice, the clinical care of patients has improved significantly. Such remarkable advancements have been achieved in the diagnostic, technological, material, imaging, as well as treatment aspects of dentistry and have become the new paradigm of orthodontics.

Moreover, three-dimensional (3D) imaging systems such as Cone Beam Computed Tomography (CBCT) have become an invaluable asset for diagnosis and treatment planning. In addition to assisting, CBCT has become vital in surgical orthodontics for planning orthognathic surgery and generating 3D printed splints and surgical plates for fixation.

Along with the diagnostic aspects, a major paradigm shift in orthodontics has occurred in treatment planning and execution. One such advancement is in-house manufacturing and 3D printing with Computer-aided design (CAD) and Computer-aided manufacturing (CAM). 3D printing has been used widely in the orthodontic field for generating aligners and dental models. In time-sensitive procedures such as auto-transplantation, 3D printing of an impacted tooth can be undertaken to create a custom trough to receive the tooth prior to extraction of the impacted tooth and thus decreasing the time outside the oral cavity and improving the success rates. The use of mini-implants and mini-plates in orthodontics has led to the development of newer treatment options such as mini-implant supported palatal expansion, mini-implant supported intermaxillary elastics for class III malocclusion, posterior intrusion for open-bite cases, as well as mini-implant supported functional appliances for class II malocclusion.

This Special Issue aims to bring together the advances in diagnostic aspects, new technology, advances in treatment planning, treatment execution, treatment evaluation, and applications of cutting-edge technology such as artificial intelligence and robotics in the field of orthodontics. As remarkable advancements have been made in the orthodontics, it is imperative for dentists and specialists to be informed and knowledgeable about the current developments. We welcome both original research and review articles.

Potential topics include but are not limited to the following:

• Applications of genetics in orthodontics
• Advances in imaging systems to decrease radiation exposure such as 180 degrees CBCT in orthodontics
• Current advances and applications of CBCT in orthodontics
• Development of bonding agents
• CAD-CAM technology in orthodontics
• New paradigms such as 3D printing in orthodontics
• 3D printing of orthodontic appliances
• Direct-to-print aligners
• Artificial intelligence-based evaluation of cephalometric radiographs
• Recent orthodontic advancements such as mini-screw assisted rapid palatal expansion
• Advances in orthodontic aligners thermoplastic materials