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Cardiovascular Development and Disease Research Area

Call for Papers

BioMed Research International is calling for submission of high-quality basic and translational research on cardiac development and disease. Abnormal cardiac development and structure malformation play a pivotal role during the pathogenesis of congenital heart disease, the most common type of human birth defect. Despite the prevalence, origins of majority of these defects are currently unknown. Advances in genetic profiling in both human and animal models have greatly expanded our knowledge of understanding signaling pathways and genetic networks regulating cardiac development. A variety of high resolution imaging modalities applied at clinical and laboratory settings revealed complex morphological and mechanical aspects of normal as well as abnormal cardiogenesis. Meanwhile, we are facing the challenges of how to elucidate the underlying mechanisms of cardiac malformations that lead to congenital heart defects and more importantly how to prevent and ultimately repair them.

This special issue invites submission of original research articles covering cardiac development and related cardiac diseases. Review articles describing the current state of the art in cardiac development and disease research field are also encouraged to submit.

Potential topics include but are not limited to the following:

  • Heart development
  • Congenital heart disease
  • Gene expression and regulation
  • Genetics and genome
  • Cardiac imaging
  • Heart regeneration and repair
  • Animal models of cardiac development and diseases
  • Mechanobiology of cardiac development
  • Computational fluid dynamics modeling of cardiogenesis
  • In vitro cardiac development models

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 13 April 2018
Publication DateAugust 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

Lead Guest Editor

  • Yonghe Ding, Mayo Clinic College of Medicine, Scottsdale, USA

Guest Editors