BioMed Research International

Extreme Environmental Stresses Induced Biological Effects: From Phenotype to Molecular Mechanisms


Publishing date
01 Aug 2020
Status
Closed
Submission deadline
10 Apr 2020

Lead Editor

1Institute of Zoology, Chinese Academy of Sciences, Beijing, China

2Gunma University Heavy Ion Medical Center, Gunma, Japan

3Division of Biological Science and Technology, Yonsei University, Wonju city, Republic of Korea

4Institute of Environmental Systems Biology, Dalian Maritime University, Dalian, China

5China Astronaut Research and Training Center, Beijing, China

This issue is now closed for submissions.
More articles will be published in the near future.

Extreme Environmental Stresses Induced Biological Effects: From Phenotype to Molecular Mechanisms

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Extreme environmental stresses, such as radiation, microgravity, hypergravity, abnormal magnetic field, and hypoxia, are generally considered to be important abiotic stress factors associated with various human health risks. When living organisms are exposed to extreme environmental stresses, a series of adverse biological responses will be triggered from molecular level, through to cell and body level. For example, microgravity and radiation exposure increases chromosomal aberration frequencies, impairs immune function, results in a loss of cardiovascular capacity, and induces bone and muscle loss in mammals, including humans. Despite a great number of studies analyzing the biological effects of extreme environmental stresses on various living systems, few of these have focused on the underlying mechanisms mediating the stress response. In recent years, the development of omics-based technologies has provided new opportunities to study the biological responses and mechanisms under extreme environmental stresses. Adaption mechanisms for biomedical protection in human or animal cells may also be studied.

This special issue is dedicated to understanding the impacts of these extreme environmental stresses on a wide range of cells. The focus is to clarify the molecular mechanisms by which the organisms respond and adapt to the extreme environment. Submissions concerning plants and animals are also welcome as long as their current or potential applications to biomedicine can be demonstrated. The special issue particularly encourages submissions relating to the underlying transcriptomic, epigenetic, proteomic, metabolomic, and microbiomic profiles, etc., under extreme environmental stresses. New methods and technologies with applications to human biomedical research will also be considered, as will both research and review articles.

Potential topics include but are not limited to the following:

  • Adverse biological effects and adaption responses induced by extreme environmental stresses, including radiation, microgravity, hypergravity, abnormal magnetic field, and hypoxia in living organisms, especially in mammalian cells
  • Spaceflight and/or ground-based simulated experiments related to molecular and cell biology
  • Metabolic profile in response to extreme environmental stresses
  • Genomic or DNA methylation in response to extreme environmental stresses
  • Gene expression and proteomic profiles in response to extreme environmental stresses
  • Microbiomics profile in response to extreme environmental stresses
  • Methodological and theoretical discussions on the relations between extreme environmental stresses and biomedical countermeasures
  • Risk assessment of extreme environmental stresses

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 4834965
  • - Review Article

The Determinant of DNA Repair Pathway Choices in Ionising Radiation-Induced DNA Double-Strand Breaks

Lei Zhao | Chengyu Bao | ... | Yeqing Sun
  • Special Issue
  • - Volume 2020
  • - Article ID 7164230
  • - Review Article

Extreme Environmental Stress-Induced Biological Responses in the Planarian

Zhonghong Cao | Hongjin Liu | ... | Xiufang Zhang
  • Special Issue
  • - Volume 2020
  • - Article ID 2641324
  • - Research Article

Microgravity versus Microgravity and Irradiation: Investigating the Change of Neuroendocrine-Immune System and the Antagonistic Effect of Traditional Chinese Medicine Formula

Haoru Zhu | Lin Zhang | ... | Ming Xie
  • Special Issue
  • - Volume 2020
  • - Article ID 9458983
  • - Research Article

TRPM7 Upregulate the Activity of SMAD1 through PLC Signaling Way to Promote Osteogenesis of hBMSCs

Fanfan Hong | Shali Wu | ... | Jinfu Wang
  • Special Issue
  • - Volume 2020
  • - Article ID 3214186
  • - Research Article

α1-Adrenergic Receptor Blockade by Prazosin Synergistically Stabilizes Rat Peritoneal Mast Cells

Nozomu Abe | Hiroaki Toyama | ... | Itsuro Kazama
  • Special Issue
  • - Volume 2020
  • - Article ID 7472618
  • - Research Article

A Static Magnetic Field Inhibits the Migration and Telomerase Function of Mouse Breast Cancer Cells

Zhu Fan | Pingdong Hu | ... | Tao Lu
  • Special Issue
  • - Volume 2020
  • - Article ID 4703286
  • - Review Article

Space Radiation Biology for “Living in Space”

Satoshi Furukawa | Aiko Nagamatsu | ... | Akihisa Takahashi
  • Special Issue
  • - Volume 2020
  • - Article ID 5358181
  • - Research Article

Dielectrophoresis-Based Method for Measuring the Multiangle Mechanical Properties of Biological Cells

Botao Zhu | Wanting Li | ... | Hao Yang
  • Special Issue
  • - Volume 2020
  • - Article ID 5762932
  • - Research Article

Transcriptome Analysis Reveals the Negative Effect of 16 T High Static Magnetic Field on Osteoclastogenesis of RAW264.7 Cells

Ting Huyan | Hourong Peng | ... | Peng Shang
  • Special Issue
  • - Volume 2020
  • - Article ID 2796510
  • - Research Article

Physiological Acclimatization of the Liver to 180-Day Isolation and the Mars Solar Day

Hailong Chen | Ke Lv | ... | Yinghui Li
BioMed Research International
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