Cardiovascular disease (CVD) is a class of diseases that usually result from malfunctions in coronary arteries and has been the leading cause of morbidity and mortality globally for many years. Interventional therapy of CVD with cardiovascular stents or vascular bypass with artificial blood vessels has emerged as the typical clinical methods of treatment. These treatment methods exhibit multifunctionalities as a result of their material properties—including mechanical properties, biocompatibility, and biodegradability—and these have been shown to play essential roles following the implantation. It is therefore an urgent problem for cardiovascular treatment to ensure that these growing clinical needs are met when designing novel biomaterials. In addition, surface modification techniques can contribute a lot to enhancing biomaterials’ biocompatibility effectively, such as via anticoagulation, antihyperplasia, anti-inflammation, and proendothelialization. However, the interaction of the related cells and biomaterials in these physiological, pathological, and therapeutic processes is still unclear and should be investigated deeply and systematically.

This special issue intends to host a variety of topics related to the aforementioned aspects. Both original research and review submissions concerning interventional cardiology related biomaterials, including design, surface modification, one or more functions' improvement, and cell/material interaction, are welcomed. Clinical case reports or utilization of novel interventional devices in the research design are also welcomed. In addition, submissions discussing environmental responsive hydrogels and multifunctional nanoparticles with potential application for interventional cardiology are also encouraged.

Potential topics include but are not limited to the following:

• Cardiovascular stents
• Nanotechnology-based advancements in interventional cardiovascular biomaterials
• Scaffolds for vascular grafts
• Surface modification of cardiovascular biomaterials
• Interaction of cardiovascular tissue/cells and biomaterials
• Environmentally responsive hydrogels for cardiovascular tissue repair