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Behavioural Neurology
Volume 7, Issue 3-4, Pages 117-122

Psychiatric Sequelae of Organophosphorous Poisoning: A Case Study and Review of the Literature

R. H. Bradwell1,2

1Department of Psychiatry, Doncaster Royal Infirmary, Doncaster, UK
2Department of Psychiatry, Burnley General Hospital, Casterton Avenue, Burnley BB10 2PQ, UK

Received 12 April 1994; Accepted 20 October 1994

Copyright © 1994 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This is the case of a young farm worker presenting with episodes of acute organic psychosis superimposed on a state of chronic anergy and hypersomnia. It is suggested that he developed an encephalopathic illness presenting with an organic bipolar affective disorder as a result of organophosphate exposure. In proposing this aetiology, an hypothesis is developed which links clinical observations and investigative results with research findings in relation to organophosphorus compounds and neuropharmacology.