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Behavioural Neurology
Volume 11 (1998), Issue 1, Pages 21-28
http://dx.doi.org/10.1155/1998/728634

Electric Source Localization Adds Evidence for Task-Specific CNVs

Ina M. Tarkka1 and Luis F. H. Basile2

1Brain Research and Rehabilitation Center Neuron, Kuopio, Finland
2Department of Psychiatry, University of Sao Paulo Medical School, Sao Paulo, Brazil

Received 1 March 1997; Accepted 19 February 1998

Copyright © 1998 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This study was an attempt to replicate recent magnetoencephalographic (MEG) findings on human task-specific CNV sources (Basile et al., Electroencephalography and Clinical Neurophysiology 90, 1994, 157–165) by means of a spatio-temporal electric source localization method (Scherg and von Cramon, Electroencephalography and Clinical Neurophysiology 62, 1985, 32–44; Scherg and von Cramon, Electroencephalography and Clinical Neurophysiology 65, 1986, 344-360; Scherg and Berg, Brain Electric Source Analysis Handbook, Version 2). The previous MEG results showed CNV sources in the prefrontal cortex of the two hemispheres for two tasks used, namely visual pattern recognition and visual spatial recognition tasks. In the right hemisphere, the sources were more anterior and inferior for the spatial recognition task than for the pattern recognition task. In the present study we obtained CNVs in five subjects during two tasks identical to the MEG study. The elicited electric potentials were modeled with four spatio-temporal dipoles for each task, three of which accounted for the visual evoked response and one that accounted for the CNV. For all subjects the dipole explaining the CNV was always localized in the frontal region of the head, however, the dipole obtained during the visual spatial recognition task was more anterior than the one obtained during the pattern recognition task. Thus, task-specific CNV sources were again observed, although the stable model consisted of only one dipole located close to the midline instead of one dipole in each hemisphere. This was a major difference in the CNV sources between the previous MEG and the present electric source analysis results. We discuss the possible basis for the difference between the two methods used to study slow brain activity that is believed to originate from extended cortical patches.