Behavioural Neurology

Behavioural Neurology / 2012 / Article

Short Communication | Open Access

Volume 25 |Article ID 720595 |

Frédéric Assal, Marina Laganaro, Corinne Dubois Remund, Claire Ragno Paquier, "Progressive Crossed-Apraxia of Speech as a First Manifestation of a Probable Corticobasal Degeneration", Behavioural Neurology, vol. 25, Article ID 720595, 5 pages, 2012.

Progressive Crossed-Apraxia of Speech as a First Manifestation of a Probable Corticobasal Degeneration

Received06 Aug 2012
Accepted06 Aug 2012


We present the longitudinal neurolinguistic, neuropsychological and neurologic follow-up of a 64 y.o. right-handed woman, who developed progressive apraxia of speech (PAOS), followed by peripheral agraphia then a left corticobasal syndrome (CBS). Neuroimaging (CT, MRI and FDG-PET) unequivocally showed progressive right hemispheric atrophy and hypometabolism. This particular evolution first confirms that PAOS is a phenotype of probable corticobasal degeneration (CBD). More importantly, this case underpins the neural organisation of motor planning processing in relation with speech, as well as graphic and limb praxis impairments, and constitutes a rare example of crossed-PAOS.

Copyright © 2012 Hindawi Publishing Corporation and the authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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