Clinical Study

Dopamine Treatment and Cognitive Functioning in Individuals with Parkinson’s Disease: The “Cognitive Flexibility” Hypothesis Seems to Work

Table 1

Sociodemographic and clinical characteristics of participants in the PD and control groups.

Individuals with PD Normal controls (1, 38) level

Gender (F/M)11/99/11
Mean (SD)
Age (years)68.8 (7.6)65.5 (8.0)1.8 >0.10
Years of formal education10.3 (4.7)12.1 (3.5)1.9>0.10
MMSEa score27.6 (1.8; range: 25–30)29.4 (1.4; range: 25–30)11.6<0.01
UPDRSb score (off state)16.6 (7.5)
Years of disease duration 2.43 (1.9; range 0.08–5)
Age at disease onset66.4 (7.4)

MMSE: Mini Mental State Examination; bUPDRS: Unified Parkinson’s Disease Rating Scale.