rTMS in the Treatment of Drug Addiction: An Update about Human Studies

Table 3

Summary of the studies on rTMS in the treatment of cocaine addiction.

Study	𝑁 subjects	Place of stimulation	Number of sessions	Length	Frequency	Intensity of stimulation	Sham stimulation	Assessment	Findings
Camprodon et al. (2007) [55]	6	Bilateral DLPFC	2 sessions	20 trains of 10 s	10 Hz	90% MT	No	Craving, anxiety, happiness, sadness, and discomfort, assessed by VAS	Reduction in craving (with right DLPFC rTMS); reduction in anxiety after right-sided rTMS; increase in happiness after right-sided and in sadness after left-sided rTMS; increase in discomfort equally by left- and right-sided stimulation
Politi et al. (2008) [56]	36	Left DLPFC	10 daily sessions	20 trains of 2 s	15 Hz	100% MT	No	Clinical assessment of craving related symptoms	Reduction in craving

DLPFC: dorsolateral prefrontal cortex; MT: motor threshold; VAS: visual analogue scale.