Transcranial Magnetic Stimulation to Address Mild Cognitive Impairment in the Elderly: A Randomized Controlled Study
Table 7
Comparison of the statistically significant neuropsychological outcomes.
T0
T1
T2
p-value
Mean
SD
Mean
SD
Mean
SD
T0 × T1
T1 × T2
T0 × T2
RBMT
Active rTMS
20.87
2.10
22.60
1.68
22.87
1.36
Sham
21.58
1.77
22.16
1.57
22.11
1.29
Group effect
0.042
0.593
0.029
Logical memory II (delayed)
Active rTMS
21.87
6.40
21.67
6.79
25.47
6.56
Sham
17.58
7.50
22.68
6.44
26.89
6.81
Group effect
0.033
0.821
0.002
Letter-number sequencing test
Active rTMS
10.20
2.08
9.80
1.74
10.87
2.36
Sham
9.16
2.57
9.74
2.08
9.32
2.79
Group effect
0.130
0.039
0.489
Trail making test B
Active rTMS
99.13
29.26
107.13
47.87
95.40
31.58
Sham
110.89
49.31
93.79
30.84
107.32
46.45
Group effect
0.036
0.023
0.988
Verbal fluency/animal naming
Active rTMS
18.47
4.49
18.00
5.66
18.80
5.65
Sham
15.95
3.66
17.58
4.69
19.00
5.08
Group effect
0.095
0.613
0.029
Analysis performed with two-way ANOVA for repeated measures (p > 0.05); statistically significant group effect; SD: standard deviation; timing of procedures: T0: baseline cognitive assessment before 1st rTMS; T1: 2nd cognitive assessment (after 10th rTMS session); T2: 3rd cognitive assessment (30 days after T1).
