Review Article

Recent Insights on Prevalence and Corelations of Hypoactive Delirium

Table 1

HD in anesthesia and cardiac surgery.

Study,
mean age in years
Diagnosis of deliriumSubtypingSummary of findings

Ceriana et al., 2010 [23] (step-down unit)18,
74.7
CAM-ICU, ICDSCCriteria used by Panharipande et al.61.1% HD

Stransky et al., 2011 [24]
(cardiac surgery)
54,
71.1 mean age for HD patients
CAM -ICU, ICDSCRASSHD 77.8%
Comparisons were made between HD patients and nondelirious subjects. Higher hemoglobin before surgery was associated with a lower prevalence of HD. HD was an independent predictor for prolonged mechanical ventilation time and ICU stay. A history of depression, duration of aortic clamping, the use of extracorporeal circulation, and preoperative medication with diuretics were predictors of HD after cardiac surgery whereas medication with b-blockers was associated with a significant lower prevalence of HD

Shaughnessy, 2013 [25] (cardiothoracic critical care unit)23,
age not available
CAM-ICURASS73.9% HD

McPherson et al., 2013 [26] (cardiovascular ICU)53,
mean age not available
CAM-ICURASSHD 91%
In most cases the duration of delirium was less than 1 day
Benzodiazepine use at admission was independently predictive of a 3-fold increased risk of an episode of delirium

Card et al., 2014 [27]
(anesthesia)
124,
57
CAM-ICURASSHD 56% at admission; 92% during stay in the PACU
High opioid doses contributed to additional sedation, thus potentially contributing to HD features

CAM-ICU: Confusion Assessment Method for the Intensive Care Unit.
RASS: Richmond Agitation-Sedation Scale.
PACU: Postanesthesia Care Unit.
ICDSC: Intensive Care Delirium Screening Checklist.
HD: hypoactive delirium.
ICU: Intensive Care Unit.