Effects of Different Types of Cognitive Training on Cognitive Function, Brain Structure, and Driving Safety in Senior Daily Drivers: A Pilot Study

Table 5

Summary of regional gray matter volume changes detected by the voxel-based morphometry analysis.

Area	MNI peak coordinates (mm)				value	Cluster
						Raw size (mm^3)	value
Increase (Post > Pre) in Group V
OFC/IFG	L	−24	26	−27	8.33	311	0.033
Increase (Post > Pre) in Group P
MFG	R	33	45	3	18.24	807	0.003
SOG	L	−18	−78	21	7.25	358	0.025
Increase (Post > Pre) in Group C
DLPFC	L	−24	42	34	8.70	192	0.033
Decrease (Pre > Post) in Group C
Precuneus	L	−3	−66	39	22.65	6446	0.002
Cerebellum	L	−6	−78	−24	12.10	4516	0.002
Caudate	R	14	−13	21	8.76	196	0.039
Larger increase in Group P compared with Group C
Extranuclear/caudate	R	15	−6	−12	4.65	5670	0.032

MNI: Montreal Neurological Institute; OFC: orbitofrontal cortex; IFG: inferior frontal gyrus; MFG: middle frontal gyrus; SOG: superior occipital gyrus; DLPFC: dorsolateral prefrontal cortex.
P values were family-wise error corrected for multiple comparisons with the nonisotropic adjusted cluster level [59] with an underlying voxel level of P < 0.001.