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Behavioural Neurology
Volume 2015, Article ID 620143, 10 pages
http://dx.doi.org/10.1155/2015/620143
Review Article

Toxicant Exposure and Bioaccumulation: A Common and Potentially Reversible Cause of Cognitive Dysfunction and Dementia

1Faculty of Medicine at the University of Calgary, Calgary, AB, Canada T2N 4N1
2Faculty of Medicine at the University of Saskatchewan, Saskatoon, SK, Canada S7N 5E5

Received 25 November 2014; Revised 31 December 2014; Accepted 31 December 2014

Academic Editor: Gianfranco Spalletta

Copyright © 2015 Stephen J. Genuis and Kasie L. Kelln. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [21 citations]

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  • Catharyn T. Liverman, Dan G. Blazer, and Kristine Yaffepp. 1–330, 2015. View at Publisher · View at Google Scholar
  • Mark Laidlaw, Dominic Rowe, Andrew Ball, and Howard Mielke, “A Temporal Association between Accumulated Petrol (Gasoline) Lead Emissions and Motor Neuron Disease in Australia,” International Journal of Environmental Research and Public Health, vol. 12, no. 12, pp. 16124–16135, 2015. View at Publisher · View at Google Scholar
  • Gerry K. Schwalfenberg, and Stephen J. Genuis, “Vitamin D, Essential Minerals, and Toxic Elements: Exploring Interactions between Nutrients and Toxicants in Clinical Medicine,” The Scientific World Journal, vol. 2015, pp. 1–8, 2015. View at Publisher · View at Google Scholar
  • Michael Nehls, “Unified theory of Alzheimer’s disease (UTAD): implications for prevention and curative therapy,” Journal of Molecular Psychiatry, vol. 4, no. 1, 2016. View at Publisher · View at Google Scholar
  • Gianluca Rizzo, and Luciana Baroni, “Health and ecological implications of fish consumption: A deeper insight,” Mediterranean Journal of Nutrition and Metabolism, vol. 9, no. 1, pp. 7–22, 2016. View at Publisher · View at Google Scholar
  • Nicole Bijlsma, and Marc Cohen, “Environmental Chemical Assessment in Clinical Practice: Unveiling the Elephant in the Room,” International Journal of Environmental Research and Public Health, vol. 13, no. 2, pp. 181, 2016. View at Publisher · View at Google Scholar
  • Lina Chouchene, Elisabeth Pellegrini, Marie-Madeleine Gueguen, Nathalie Hinfray, François Brion, Benjamin Piccini, Olivier Kah, Khaled Saïd, Imed Messaoudi, and Farzad Pakdel, “Inhibitory effect of cadmium on estrogen signaling in zebrafish brain and protection by zinc,” Journal of Applied Toxicology, 2016. View at Publisher · View at Google Scholar
  • Claudia Escudero-Lourdes, “Toxicity mechanisms of arsenic that are shared with neurodegenerative diseases and cognitive impairment: Role of oxidative stress and inflammatory responses,” NeuroToxicology, 2016. View at Publisher · View at Google Scholar
  • Stephen J. Genuis, Kevin Lane, and Detlef Birkholz, “Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study,” BioMed Research International, vol. 2016, pp. 1–10, 2016. View at Publisher · View at Google Scholar
  • Mark A.S. Laidlaw, Gabriel M. Filippelli, Sally Brown, Jorge Paz-Ferreiro, Suzie M. Reichman, Pacian Netherway, Adam Truskewycz, Andrew S. Ball, and Howard W. Mielke, “Case studies and evidence-based approaches to addressing urban soil lead contamination,” Applied Geochemistry, vol. 83, pp. 14–30, 2017. View at Publisher · View at Google Scholar
  • Pallavi P. Tonsekar, Shuying S. Jiang, and Gang Yue, “Periodontal disease, tooth loss and dementia: Is there a link? A systematic review,” Gerodontology, 2017. View at Publisher · View at Google Scholar
  • Jelena Čulin, “Brominated flame retardants: Recommendation for different listing under the Hong Kong Convention,” Science of the Total Environment, vol. 636, pp. 919–926, 2018. View at Publisher · View at Google Scholar
  • Brahim Gargouri, Nizar M. Yousif, Abdelraheim Attaai, Michèle Bouchard, Yassine Chtourou, Bernd L. Fiebich, and Hamadi Fetoui, “Pyrethroid bifenthrin induces oxidative stress, neuroinflammation, and neuronal damage, associated with cognitive and memory impairment in murine hippocampus,” Neurochemistry International, 2018. View at Publisher · View at Google Scholar
  • Safa Ben Mimouna, Sana Boughammoura, Marouane Chemek, Zohra Haouas, Mohamed Banni, and Imed Messaoudi, “Disruption of the zinc metabolism in rat fœtal brain after prenatal exposure to cadmium,” Chemico-Biological Interactions, 2018. View at Publisher · View at Google Scholar
  • Seth A. Gale, Diler Acar, and Kirk R. Daffner, “Dementia,” The American Journal of Medicine, 2018. View at Publisher · View at Google Scholar
  • Sonia Dagnino, “Unravelling the Exposome: Conclusions and Thoughts for the Future,” Unraveling the Exposome, pp. 425–437, 2018. View at Publisher · View at Google Scholar
  • Honeylene Ongy, and Beatriz Belonias, “Lead potential bioaccumulation in two species of commonly used medicinal plants in Leyte,” Annals of Tropical Research, pp. 1–14, 2018. View at Publisher · View at Google Scholar
  • Nemi Malhotra, Jung-Ren Chen, Sreeja Sarasamma, Gilbert Audira, Petrus Siregar, Sung-Tzu Liang, Yu-Heng Lai, Geng-Ming Lin, Tzong-Rong Ger, and Chung-Der Hsiao, “Ecotoxicity Assessment of Fe3O4 Magnetic Nanoparticle Exposure in Adult Zebrafish at an Environmental Pertinent Concentration by Behavioral and Biochemical Testing,” Nanomaterials, vol. 9, no. 6, pp. 873, 2019. View at Publisher · View at Google Scholar
  • Qi Li, Jianqin Yuan, Ruiyan Niu, and Jundong Wang, “Fluoride exposure decreased learning ability and the expressions of the insulin receptor in male mouse hippocampus and olfactory bulb,” Chemosphere, vol. 224, pp. 71–76, 2019. View at Publisher · View at Google Scholar
  • Menizibeya O. Welcome, “Gut Microbiota Disorder, Gut Epithelial and Blood–Brain Barrier Dysfunctions in Etiopathogenesis of Dementia: Molecular Mechanisms and Signaling Pathways,” NeuroMolecular Medicine, 2019. View at Publisher · View at Google Scholar
  • Ronghui Zheng, Yusheng Zhang, Chao Fang, Mengyun Chen, Fukun Hong, and Jun Bo, “Joint effects of chronic exposure to environmentally relevant levels of nonylphenol and cadmium on the reproductive functions in male rockfish Sebastiscus marmoratus,” Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol. 215, pp. 25–32, 2019. View at Publisher · View at Google Scholar