Clinical Study

The Interactive Relationship between Pain, Psychosis, and Agitation in People with Dementia: Results from a Cluster-Randomised Clinical Trial

Table 1

Sample characteristics of patients at baseline.

Control ()Intervention ()df

Age (SD) 86.5 (6.7)84.9 (7.0)350 0.022
Women (%)131 (74.0)131 (74.9)10.856
FAST (SD)6.0 (0.7)6.1 (0.7)3490.057
MMSE (SD)8.4 (6.7)7.5 (6.5)3460.177
Barthels ADL total score (SD)8.6 (5.6)7.9 (5.7)3390.216
CMAI total score (SD)56.2 (16.1)56.5 (15.2)3490.487
MOBID-2 (SD)3.7 (2.5)3.8 (2.7)3250.988
Medications (SD)3.6 (1.6)3.4 (2.1)3180.146
 Analgesics (%)122 (68.9)117 (66.9)10.404
  Paracetamol (%)94 (53.1)99 (56.6)10.665
  Opioids (%)51 (28.8)43 (24.6)10.292
 NSAIDS (%)9 (5.1)13 (7.4)10.364
 Psycholeptics (%)112 (63.3)104 (59.4)10.458
  Antipsychotics (%)13 (7.3)17 (9.7)10.465
  Anxiolytics (%)86 (48.6)80 (45.7)10.589
Psychosis symptoms (%)71 (20.2)83 (23.6)10.209
Delusion (%)49 (27.7)66 (37.7)10.056
Hallucination (%)29 (16.4)32 (18.3)10.690
Euphoria (%)15 (8.5)16 (9.1)10.864
Agitation symptoms (%)128 (36.4)137 (38.9)10.285
Agitation/aggression (%)74 (41.8)85 (48.6)10.253
Disinhibition (%)56 (31.6)59 (33.7)10.760
Irritability (%)84 (47.5)85 (48.6)10.956
Aberrant motor behaviour (%)57 (32.2)65 (37.1)10.388

Independent-samples -test.
Pearson’s Chi-squared test.
Mann-Whitney test.