Research Article

Efficacy of a Computer-Assisted Cognitive Rehabilitation Intervention in Relapsing-Remitting Multiple Sclerosis Patients: A Multicenter Randomized Controlled Trial

Table 5

Comparison of neuropsychological test scores for the standard care MS control group at baseline and posttreatment.

BaselinePosttreatmentBaseline versus posttreatment
z-score
valuesEffect size

MeanMedianMeanMedian
SRTLTS36.4236.5036.3837.000.1870.8520.026
SRTDR7.157.007.127.000.3020.7630.042
BVMT-RT22.5022.0020.8021.100.3040.6750.034
VFT phon29.8128.0029.9528.50−2.3650.0180.328
VFT sem40.5039.5039.5838.50−2.8740.0040.399
SDMT37.4238.5037.4339.00−0.0690.9450.010
TMT-A60.2757.0060.8858.50−2.1170.0340.294
TMT-B111.54110.00110.96107.501.0420.2980.144
SNST58.7057.4059.1057.600.3480.7800.035

Notes: All values are raw scores. and . Wilcoxon signed-ranked nonparametric test used for comparison of medians between baseline and posttreatment. SRTLTS: Selective Reminding Test Long-Term Storage; SRTDR: Selective Reminding Test-Delayed Recall; BVMT-RT: Brief Visuospatial Memory Test-Revised Total Recall; VFT phon: Greek Verbal Fluency Test-Phonemic Fluency; VFT sem: Greek Verbal Fluency Test-Semantic Fluency; SDMT: Symbol Digit Modalities Test; TMT-A and TMT-B: Greek Trail Making Test Part A and Greek Trail Making Test Part B; SNST: Stroop Neuropsychological Screening Test.