Research Article

Neuroprotective and Antiamnesic Effects of Mitragyna inermis Willd (Rubiaceae) on Scopolamine-Induced Memory Impairment in Mice

Table 1

Effect of M. inermis in normal mice in EPM.

TreatmentsTransfer latency (seconds)Inflexion ratio
8th day9th day

H2O69.6 ± 9.963.2 ± 2.20.10
39.369.6 ± 7.543 ± 2.40.62
98.2563.0 ± 6.033.4 ± 1.50.89
196.566.2 ± 6.234.4 ± 5.40.92
39361.6 ± 6.338.4 ± 3.90.60
Pira60.6 ± 3.832.6 ± 4.60.86

Data are mean ± SD, per dose. , , and , compared to control group (H2O), one-way ANOVA followed by Dunnett’s bilateral comparisons for TL, and Duncan’s test for IR. H2O: distilled water, Pira: piracetam 200 mg/kg.