Cerebral Reorganization in Subacute Stroke Survivors after Virtual Reality-Based Training: A Preliminary Study

Table 3

Significant activated areas (, corrected for multiple comparisons across the whole brain volume) during active movement of the paretic ankle and areas with a significant difference in activation () between pre- and posttherapy.

Activated areas	Maximum Z-score	MNI coordinates
		x	y	z
Pretherapy
SMC
Ipsilesional	3.53	−9	−33	72
Contralesional	2.77	3	−36	69
SMA
Ipsilesional	2.37	−2	0	63
Contralesional	3.02	6	0	54
Posterior cerebellum
Contralesional	2.95	24	−63	−15
Supramarginal gyrus
Ipsilesional	3.61	−63	−30	30
Contralesional	2.60	54	−29	26
Posttherapy
SMC
Ipsilesional	3.64	−9	27	76
Contralesional	3.04	2	−24	72
SMA
Ipsilesional	3.50	−2	−3	60
Contralesional	3.43	6	0	63
Cingulate motor area
Ipsilesional	2.39	−3	−3	48
Contralesional	2.31	6	0	42
Posterior cerebellum
Ipsilesional	3.01	−27	−60	−24
Contralesional	3.09	21	−63	−15
Anterior cerebellum
Ipsilesional	2.53	−15	−48	−18
Contralesional	2.50	18	−54	−15
Posttherapy versus pretherapy
SMC
Ipsilesional	2.60	−12	−18	76
SMA
Ipsilesional	2.66	−6	0	66
Ipsilesional	2.97	6	6	63