Clinical Study

COGEVIS: A New Scale to Evaluate Cognition in Patients with Visual Deficiency

Table 1

Description of the population comparing participants with normal cognition (NC) to cognitively impaired (CI) ones.

NC ()CI () value

Age69.1 (1.7)75.0 (2.2)0.04
Gender: female9 (45)7 (58.3)0.5
Years of education11.8 (1)7.9 (1.3)0.02
Right handedness15 (75)12 (100)0.12
MMSE26.1 (0.8)20.1 (1)0.0001
FAB14.9 (0.6)10.8 (0.7)0.0001
Digit span forward5.8 (0.2)4.7 (0.3)0.005
Digit span backward4.2 (0.2)3.2 (0.3)0.03
CVLT total recall score53.2 (2.4)33.2 (2.1)0.0001
Intrusions0.8 (0.6)3.1 (0.7)0.02
Recognition15.2 (0.5)12.6 (0.7)0.008
False recognition0.6 (0.6)4.3 (0.8)0.02
Categorical (animals) fluency29.0 (2.1)18 (2.7)0.004
Lexical (letter P) fluency21.4 (1.8)12.8 (2.4)0.008
WAIS-IV vocabulary10.7 (0.7)7.0 (0.8)0.003
Symbolic praxis4.9 (0.1)4.6 (0.2)0.06
Pantomime praxis9.8 (0.3)8.9 (0.3)0.04
MADRS13.3 (2.4)17.5 (3.3)0.3
Baseline COGEVIS27.5 (0.6)22.9 (0.8)0.0001
Follow-up COGEVIS28.4 (0.9)21.7 (1.1)0.0002
Visual deficiency duration (years)8.1 (1.9)7.6 (2.5)0.9
Best-seeing eye visual acuity0.13 (0.02)0.10 (0.03)0.6
IADL14.2 (1.2)20.6 (1.5)0.002
NEI VFQ 2535.8 (2.9)28.4 (3.6)0.12

Values expressed as mean (SEM) and t-tests performed for continuous variable or N (%) and chi-squared test performed for categorical variables. CVLT: California Verbal Learning Test; FAB: Frontal Assessment Battery; IADL: Lawton’s Instrumental Activities of Daily Living; MADRS: Montgomery–Åsberg Depression Rating Scale; MMSE: Mini Mental State Examination; NEI VFQ 25: National Eye Institute Visual Function Questionnaire; WAIS-IV: Wechsler Adult Intelligence Scale—Fourth Edition.