Research Article

Improving Cognitive Function after Traumatic Brain Injury: A Clinical Trial on the Potential Use of the Semi-Immersive Virtual Reality

Table 4

Post hoc analysis of clinical scores between baseline (T0) and follow-up (T1), for both the Virtual Reality Training Group (VRTG) and the Traditional Cognitive Rehabilitation Group (TCRG).

Clinical assessmentVRTG valueTCRG value
T0T1T0T1

MoCA23.0 (21.25–24.7)27.0 (26.0–28.0)<0.00123.0 (20.0-24.7)24.0 (22.0-25.7)<0.001
HRS-D10.0 (6–13.7)5.0 (3.0–7.0)<0.00112.0 (7.25-13.0)10.0 (6.25-12.0)<0.001
HRS-A10.0 (4.25–13.7)6.0 (1.0–8.7)<0.0019.0 (5.25-11.7)7.0 (5.0-10.0)<0.001
TMT-A67.5 (55.25-100)57.0 (35.0–88.0)<0.00179.5 (57.25-168.0)74.5 (55.0-160.75)<0.001
TMT-B201.5 (130.2–274.0)145.5 (92.0–200.0)<0.001179.0 (140.0-246.5)174.0 (140.0-237.5)<0.001
TMT B-A95.5 (57.5–161.0)82.5 (40.0–115.5)<0.00182.0 (65.0-160.5)80.5 (62.5-155.0)0.4
VS34.0 (26.0–43.7)42.7 (36.8–47.2)<0.00133.6 (25.1-43.7)36.8 (27.1-46.2)0.002
FAB14.4 (11.1–15.9)17.2 (15.2–18.0)<0.00113.6 (13.0-16.3)14.9 (14.0-16.4)<0.001
WEIGL8.1 (6.3–9.2)12.1 (10.1–14.0)<0.0017.2 (4.7-10.7)8.2 (5.8-11.5)<0.001

Scores are in median (first-third quartile); significant differences are in bold. Legend: FAB: Frontal Assessment Battery; HRS-A: Hamilton Rating Scale for Anxiety; HRS-D: Hamilton Rating Scale for Depression; MoCA: Montreal Cognitive Assessment; TMT-A: Trail Making Test—Form A; TMT-B: Trail Making Test—Form B; TMT B-A: Trail Making Test—Form B-A; VS: Visual Search; WEIGL: Weigl Test.