Research Article

Retinal Levels of Amyloid Beta Correlate with Cerebral Levels of Amyloid Beta in Young APPswe/PS1dE9 Transgenic Mice before Onset of Alzheimer’s Disease

Table 1

RNFL thickness inpatients of different ages with neurodegenerative disease.

Age (years)Female : maleSubjectsCognitive evaluationRNFL thicknessReference

4926 : 23Down syndromeTemporal cortex MRI and PET[37]
6648 : 18Multiple sclerosisMRI[38]
56.0 (55.9 to 56.1)3203817172 : 14866Cognitive declineCognitive function tests[39]
5635 : 21Preclinical ADPET-0.228[41]
6332 : 31ADPET/CT[42]

; ; ; AD: Alzheimer’s disease; MRI: magnetic resonance imaging; PET: positron emission tomography; CT: computed tomography; OR: odds ratio; AUC: area under the receiver operating characteristic curves (to assess the ability of RNFL thicknesses to discriminate AD cases from healthy people).