Hypomania, Depression, Euthymia: New Evidence in Parkinson’s Disease
Table 1
Demographic and clinical data of patients with Parkinson’s disease and controls.
Patients,
DN,
DRT-patients (n-MF+MF),
n-MF,
MF,
Controls,
(d.f.)
value
Age
63.5 (9.68)
63.1 (9.93)
63.6 (9.67)
62.8 (9.50)
64.9 (9.93)
65.7 (8.51)
0.911 (3)
0.438
Age at onset
56.5 (11.15)
62.3 (10.13)
54.7 (10.91)
55.6 (11.49)
53.5 (10.26)
—
4.38 (2)
0.015
Years of disease
7.4 (6.17)
0.8 (0.87)
9.3 (5.72)
7.6 (5.06)
11.7 (5.78)
—
32.47 (2)
<0.0001
Hoehn and Yahr
1.9 (0.51)
1.6 (0.60)
2.0 (0.44)
1.9 (0.48)
2.2 (0.36)
—
8.380 (2)
0.001
UPDRS I
0.3 (0.74)
0.3 (0.46)
0.3 (0.79)
0.2 (0.60)
0.48 (1)
—
1.317 (2)
0.273
UPDRS II
4.6 (4.13)
5.8 (3.71)
4.3 (4.19)
4.0 (4.28)
4.7 (4.10)
—
1.102 (2)
0.337
UPDRS III
18. 4 (5.92)
17.1 (6.16)
18.7 (7.07)
18.1 (7.23)
19.4 (6.90)
—
0.564 (2)
0.571
UPDRS IV
1.2 (1.80)
0.00 (0)
1.5 (1.89)
0.3 (0.73)
3.0 (1.90)
—
49.04 (2)
<0.0001
Data are reported as mean (standard deviation). Legend: DN: de novo drug-naive patients; DRT patients: patients taking dopamine replacement therapy; n-MF: patients not exhibiting motor fluctuations; MF: patients exhibiting motor fluctuations; UPDRS: Unified Parkinson’s Disease Rating Scale. Significant values are in bold.
