Histopathological and Biochemical Assessment of Neuroprotective Effects of Sodium Valproate and Lutein on the Pilocarpine Albino Rat Model of Epilepsy

Figure 10

Photomicrographs of the hippocampus of albino rat group III (PLC/SVP) show (a) CA1, (b) CA3, and (c) DG. CA areas are formed of three layers: molecular layer (M) and pyramidal (P) and polymorphic (P1) layers, in CA2 and CA3 areas, occasional shrunken darkly stained pyramidal cells (↑). Dentate gyrus is formed of molecular (M) layer, granule cell layer (G), and polymorphic layers (P2). Occasional shrunken granule cells with shrunken deeply stained pyknotic nuclei (↑) are seen. Inset: higher magnification of the pyramidal cells in the CA3 area. Scale bar: 50 μm, PLC/SVP group III, H&E ×20 and inset ×40.

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