TY - JOUR
A2 - Trojano, Luigi
AU - Luca, Antonina
AU - Donzuso, Giulia
AU - D’Agate, Concetta
AU - Terravecchia, Claudio
AU - Cicero Edoardo, Calogero
AU - Mostile, Giovanni
AU - Sciacca, Giorgia
AU - Nicoletti, Alessandra
AU - Zappia, Mario
PY - 2022
DA - 2022/12/10
TI - Verbal Reasoning Impairment in Parkinson’s Disease
SP - 3422578
VL - 2022
AB - Background. The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson’s disease (PD) and healthy controls (HCs). Methods. The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets. Results. Eighty-seven PD patients (51 men; mean age 63.8±7.9 years) and 87 HCs (46 men; mean age 63.7±8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3±2.1) than HCs (12.9±1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70–0.98; p=0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70–0.98; p=0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r=0.330; p=0.002). Conclusions. PD patients presented lower VR performance than HCs.
SN - 0953-4180
UR - https://doi.org/10.1155/2022/3422578
DO - 10.1155/2022/3422578
JF - Behavioural Neurology
PB - Hindawi
KW -
ER -