TY - JOUR A2 - Trojano, Luigi AU - Luca, Antonina AU - Donzuso, Giulia AU - D’Agate, Concetta AU - Terravecchia, Claudio AU - Cicero Edoardo, Calogero AU - Mostile, Giovanni AU - Sciacca, Giorgia AU - Nicoletti, Alessandra AU - Zappia, Mario PY - 2022 DA - 2022/12/10 TI - Verbal Reasoning Impairment in Parkinson’s Disease SP - 3422578 VL - 2022 AB - Background. The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson’s disease (PD) and healthy controls (HCs). Methods. The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets. Results. Eighty-seven PD patients (51 men; mean age 63.8±7.9 years) and 87 HCs (46 men; mean age 63.7±8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3±2.1) than HCs (12.9±1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70–0.98; p=0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70–0.98; p=0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r=0.330; p=0.002). Conclusions. PD patients presented lower VR performance than HCs. SN - 0953-4180 UR - https://doi.org/10.1155/2022/3422578 DO - 10.1155/2022/3422578 JF - Behavioural Neurology PB - Hindawi KW - ER -