Research Article

Overexpression of PGC-1α Increases Fatty Acid Oxidative Capacity of Human Skeletal Muscle Cells

Figure 3

Effects of PGC-1α overexpression on palmitic acid oxidation (a) and uptake (b) in human myotubes. Myotubes infected with either empty vector or PGC-1α were incubated with [3H]palmitic acid and assayed for labeled acid soluble metabolites (ASM), as described in Section 2. (a) Values are presented as means ± SEM ( experiments, representing 3 different donors; with 3 replicates each). (b) Values are presented as means ± SEM ( experiments, representing 2 different donors; with 3 replicates each). *Significantly different from empty control vector at .
714074.fig.003a
(a)
714074.fig.003b
(b)