Inhibition of Rat Muscle and Liver Phosphofructokinases by High Doses of Ethanol

Table 3

Average free energies of binding for ADP, ATP, and ethanol with human and rat muscle and liver phosphofructokinases.

Ligand	Enzyme
	Rat muscle	Human muscle	Rat liver	Human liver
ADP	−6.011 kcal/mol	−6.016 kcal/mol	−5.724 kcal/mol	−5.637 kcal/mol
ATP	−5.375 kcal/mol	−4.413 kcal/mol	−5.255 kcal/mol	−3.623 kcal/mol
Ethanol	−1.812 kcal/mol	−1.821 kcal/mol	−1.852 kcal/mol	−1.871 kcal/mol