Inhibition of Rat Muscle and Liver Phosphofructokinases by High Doses of Ethanol

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2">Ligand</td><td align="center" colspan="4">Enzyme</td></tr><tr class="thead"><td align="center">Rat muscle</td><td align="center">Human muscle</td><td align="center">Rat liver</td><td align="center">Human liver</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left">ADP</td><td align="center">17049.58</td><td align="center">17188.33</td><td align="center">10706.98</td><td align="center">9298.64</td></tr><tr><td align="left">ATP</td><td align="center">6080.97</td><td align="center">1278.59</td><td align="center">5006.03</td><td align="center">355.28</td></tr><tr><td align="left">Ethanol</td><td align="center">18.86</td><td align="center">19.14</td><td align="center">20.13</td><td align="center">20.76</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Binding constants for ADP, ATP, and ethanol with human and rat muscle and liver phosphofructokinases.

Biochemistry Research International

tab4

Table 4

Table 4: Inhibition of Rat Muscle and Liver Phosphofructokinases by High Doses of Ethanol 