Association of a Common Variant at 10q26 and Benign Prostatic Hyperplasia Aggressiveness in Han Chinese Descent

Table 4

Effects of rs2252004 on the change of IPSS, TPV, tPSA, and fPSA after treatment in BPH case group.

Change^1	Mean change	𝛽 (SE)^2	P (Rec)^3
	AA/CA/CC
IPSS	1.38/−0.14/−0.2	1.61 (0.80)	0.045
TPV	4.62/−0.3/−0.84	5.35 (2.38)	0.025
tPSA	1.18/0.52/0.56	0.64 (0.69)	0.357
fPSA	0.37/0.12/0.05	0.28 (0.29)	0.335

1The changes of IPSS, TPV, fPSA, and tPSA were calculated using the values after treatment minus the values at baseline.
2Beta and standard error results based on nontransformed data for IPSS, TPV, tPSA, and fPSA for risk allele A using recessive model (CA/CC as the reference group).
3The P-values are analyzed under the recessive model with linear regression adjusted by age.
Data of tPSA and fPSA did not show (𝑃>0.05).