Research Article

Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine

Table 2

Representation of SPA, TAS, TOS, and OSI for cases and controls.

Subjects/parametersControl-1
( = 50)
Control-2
( = 50)
Case-1
( = 86)
Case-2
( = 43)
ANOVA
(Sig./)

SPA
(mmol min−1 L−1)
55.72 ± 7.90
( = 47.32 to 78.34)
60.18 ± 7.85
( = 45 to 82)
68.56 ± 11.09
( = 47.49 to 89.42)
74.23 ± 13.22
( = 56 to 96)
= 32.14
0.001
TAS
(mmol Trolox Eq/L)
1.97 ± 0.51
( = 0.81 to 2.91)
1.82 ± 0.43
( = 0.95 to 2.76)
1.42 ± 0.39
( = 0.78 to 2.25)
1.20 ± 0.45
( = 0.63 to 1.98)
= 32.99
0.001
TOS
(µmol H2O2 Eq/L)
13.82 ± 2.14
( = 9.88 to 17.71)
17.54 ± 2.46
( = 12.74 to 28.91)
20.13 ± 3.75
( = 12.50 to 34.0)
22.21 ± 3.66
( = 15.34 to 31.0)
= 64.47
0.001
OSI
(arbitrary unit)
8.02 ± 4.21
( = 3.41 to 21.86)
10.58 ± 4.58
( = 5.04 to 29.50)
16.04 ± 7.58
( = 5.55 to 42.50)
22.09 ± 10.21
( = 7.87 to 47.69)
= 37.21
0.001