A Polymorphism in Hepatocyte Nuclear Factor 1 Alpha, rs7310409, Is Associated with Left Main Coronary Artery Disease

Table 2

Primary information for five genotyped SNPs.

Genotyped SNP	Chr^a	Regulome DBscore^b	TFBS^c	Splicing (ESE or ESS)	Location	MAF^d for Chinese population in database	Genotyping; value, %
HNF1A, rs7310409 G/A	12	5	—	—	Intron1	0.366	99.83
CRP, rs1800947 G/C	1	6	—	—	Synonymous	0.067	99.92
CRP, rs3093059 T/C	1	No data	Y	—	5′ Near gene	0.171	99.83
MTHFR, rs1801133 C/T	1	4	—	—	Missense	0.341	99.83
MTHFD, rs1076991 A/G	14	4	Y	—	5′ UTR	0.317	99.83

^aChr: chromosome; ^bDBscore: http://www.regulomedb.org/; ^cTFBS: transcription factor binding site (http://snpinfo.niehs.nih.gov/snpinfo/snpfunc.htm); ^dMAF: minor allele frequency.